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The Use of Autologous Mesenchymal Stem Cells for Cell Therapy of Patients with Amyotrophic Lateral Sclerosis in Belarus

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Bulletin of Experimental Biology and Medicine Aims and scope

We studied a new method of treatment of amyotrophic lateral sclerosis with autologous mesenchymal stem cells. Autologous mesenchymal stem cells were injected intravenously (intact cells) or via lumbar puncture (cells committed to neuronal differentiation). Evaluation of the results of cell therapy after 12-month follow-up revealed slowing down of the disease progression in 10 patients in comparison with the control group consisting of 15 patients. The cell therapy was safe for the patients.

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Authors and Affiliations

  1. Republican Research-and-Practical Center of Neurology and Neurosurgery, Minsk, Belarus

    Yu. N. Rushkevich, G. V. Zabrodets & S. A. Likhachev

  2. Republican Research-and-Practical Center of Transfusion and Medical Biotechnologies, Minsk, Belarus

    S. M. Kosmacheva, S. I. Ignatenko, N. V. Goncharova & I. N. Severin

  3. Belorussian State Medical University, Minsk, Belarus

    M. P. Potapnev

Authors
  1. Yu. N. Rushkevich
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  2. S. M. Kosmacheva
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  3. G. V. Zabrodets
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  4. S. I. Ignatenko
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  5. N. V. Goncharova
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  6. I. N. Severin
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  7. S. A. Likhachev
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  8. M. P. Potapnev
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Corresponding author

Correspondence to Yu. N. Rushkevich.

Additional information

Translated from Kletochnye Tekhnologii v Biologii i Meditstine, No. 2, pp. 130–136, April, 2015

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Rushkevich, Y.N., Kosmacheva, S.M., Zabrodets, G.V. et al. The Use of Autologous Mesenchymal Stem Cells for Cell Therapy of Patients with Amyotrophic Lateral Sclerosis in Belarus. Bull Exp Biol Med 159, 576–581 (2015). https://doi.org/10.1007/s10517-015-3017-3

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  • DOI: https://doi.org/10.1007/s10517-015-3017-3

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