Abstract
This study focused on the difference between pre-morbid and current hand preference of patients with Parkinson’s disease (PD). A survey instrument comprised items measuring pre-morbid and current hand preference and question related to the side of occurrence of initial symptoms. These questions were administered to 471 PD patients. The results show a significant change of pre-morbid right hand preference toward using the left when the side of PD onset was on the right hand and vice versa. Disease duration does not predict the amount of hand preference shift.
References
Annett M (1970) A classification of hand preference by association analysis. Br J Psychol 61(3):303–321
Annett M, Kilshaw D (1983) Right- and left-hand skill II: estimating the parameters of the distribution of L-R differences in males and females. Br J Psychol 74(Pt 2):269–283
Barrett MJ, Wylie SA, Harrison MB, Wooten GF (2011) Handedness and motor symptom asymmetry in Parkinson’s disease. J Neurol Neurosurg & Psychiatry 82(10):1122–1124. doi:10.1136/jnnp.2010.209783
Kuhn W, Heye N, Müller T, Kraus P, Klotz P, Friedrich B, Welter FL, Przuntek H (1996) The motor performance test series in Parkinson’s disease is influenced by depression. J Neural Transm 103(3):349–354
Mohr C, Bracha HS (2004) Compound measure of hand-foot-eye preference masked opposite turning behavior in healthy right-handers and non-right-handers: technical comment on Mohr et al. (2003). Behav Neurosci 118(5):1145–1146. doi:10.1037/0735-7044.118.5.1145
Mohr C, Landis T, Bracha HS, Brugger P (2003) Opposite turning behavior in right-handers and non-right-handers suggests a link between handedness and cerebral dopamine asymmetries. Behav Neurosci 117(6):1448–1452. doi:10.1037/0735-7044.117.6.1448
Oldfield RC (1971) The assessment and analysis of handedness: the Edinburgh inventory. Neuropsychologia 9(1):97–113
Samejima F (1969) Estimation of latent ability using a response pattern of graded scores. Psychometric Monograph no 17
Samejima F (1997) Departure from normal assumptions: a promise for future psychometrics with substantive mathematical modeling. Psychometrika 62(4):471–493
Stewart KC, Fernandez HH, Okun MS, Rodriguez RL, Jacobson CE, Hass CJ (2009) Side onset influences motor impairments in Parkinson disease. Parkinsonism Relat Disord 15(10):781–783. doi:10.1016/j.parkreldis.2009.02.001
Stochl J, Boomsma A, Ruzicka E, Brozova H, Blahus P (2008) On the structure of motor symptoms of Parkinson’s disease. Mov Disord 23(9):1307–1312. doi:10.1002/mds.22029
Stochl J, Hagtvet KA, Brozova H, Klempir J, Roth J, Ruzicka E (2009) Handedness does not predict side of onset of motor symptoms in Parkinson’s disease. Mov Disord 24(12):1836–1839. doi:10.1002/mds.22653
Taylor Tavares AL, Jefferis GS, Koop M, Hill BC, Hastie T, Heit G, Bronte-Stewart HM (2005) Quantitative measurements of alternating finger tapping in Parkinson’s disease correlate with UPDRS motor disability and reveal the improvement in fine motor control from medication and deep brain stimulation. Mov Disord 20(10):1286–1298. doi:10.1002/mds.20556
Uitti RJ, Baba Y, Whaley NR, Wszolek ZK, Putzke JD (2005) Parkinson disease: handedness predicts asymmetry. Neurology 64(11):1925–1930. doi:10.1212/01.wnl.0000163993.82388.c8
van der Hoorn A, Bartels AL, Leenders KL, de Jong BM (2011) Handedness and dominant side of symptoms in Parkinson’s disease. Parkinsonism Relat Disord 17(1):58–60. doi:10.1016/j.parkreldis.2010.10.002
Yust-Katz S, Tesler D, Treves T, Melamed E, Djaldetti R (2008) Handedness as a predictor of side of onset of Parkinson’s disease. Parkinsonism Relat Disord 14(8):633–635
Acknowledgments
The authors would like to thank Professor Peter B Jones (Head of Department of Psychiatry, University of Cambridge) for his comments on the paper. This study was supported by the Czech Science Foundation, grant nr. 406/07/P513, by the Czech Ministry of Education, research projects MSM 0021620864 and MSM 0021620849, and by Internal Grant Agency of Czech Ministry of Health, grant nr. NS10336-3. TJC was supported by a Career Scientist Award from the UK Department of Health, and the NIHR Collaboration for Leadership in Applied Health Research and Care (CLAHRC) for Cambridgeshire and Peterborough.
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The authors declare that they have no conflict of interest.
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Štochl, J., Croudace, T.J., Brožová, H. et al. Changes of hand preference in Parkinson’s disease. J Neural Transm 119, 693–696 (2012). https://doi.org/10.1007/s00702-011-0759-6
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DOI: https://doi.org/10.1007/s00702-011-0759-6