Summary
Two new Schiff bases, N-4-hydroxysalicylidene-glycylglycine (K·GGRS·H2O), N-O-vanillal-glycylglycine (K· GGVS·3H2O) and their manganese(II), cobalt(II), nickel(II) and copper(II) complexes have been synthesized and characterized by elemental analysis, t.g.a., molar conductance, i.r. and u.v. spectral studies. The 13Cn.m.r. spectrum of one of the Schiff base ligands has been recorded. The results show that the ligand is coordinated to the central metal ion via amide nitrogen, imino nitrogen, phenolic oxygen and carboxyl oxygen to form a quadridentate complexes. Some of the complexes exhibit strong inhibitory action towards Candida albicans and Cryptococcus neoformans.
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Zishen, W., Zhiping, L. & Zhenhuan, Y. Synthesis, characterization and antifungal activity of glycylglycine Schiff base complexes of 3d transition metal ions. Transition Met Chem 18, 291–294 (1993). https://doi.org/10.1007/BF00207949
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DOI: https://doi.org/10.1007/BF00207949