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Biochemical and histochemical observations on β-glucuronidase in the mammalian gallbladder

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Summary

Histochemical and biochemical methods have been used to investigate the amount and distribution ofβ-glucuronidase in rabbit and guinea pig gallbladder. The enzyme, which is present in high concentration, is found in the cytoplasm of the epithelial cells. Significant species and sex differences in the amount of enzyme present occur. The possible functional significance of the enzyme in mitosis, electrolyte metabolism, and bilirubin transport is discussed.

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Author information

Authors and Affiliations

  1. From the Department of Anatomy, School of Medicine, University of Leeds, Leeds, Yorkshire, England

    Bryan Ballantyne B.Sc., M.B., Ph.D. (M.R.C.S., M.I.Biol.) & W. G. Wood B.Sc.

Authors
  1. Bryan Ballantyne B.Sc., M.B., Ph.D.
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  2. W. G. Wood B.Sc.
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Additional information

Supported by a grant from the Multiple Sclerosis Society of Great Britain and Northern Ireland.

The authors thank Mr. R. K. Adkin and Mr. R. H. Nettleton for technical assistance.

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Ballantyne, B., Wood, W.G. Biochemical and histochemical observations on β-glucuronidase in the mammalian gallbladder. Digest Dis Sci 13, 551–557 (1968). https://doi.org/10.1007/BF02233068

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  • DOI: https://doi.org/10.1007/BF02233068

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