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Drug Discovery and Evaluation

Pharmacological Assays

  • Book
  • © 1997

Overview

Editors:
  1. H. Gerhard Vogel

    1. Johann Wolfgang Goethe Universität Frankfurt, Frankfurt am Main, Germany
      Philipps Universität Marburg, Marburg, Germany

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  2. Wolfgang H. Vogel

    1. Department of Pharmacology Jefferson Medical College, Thomas Jefferson University, Philadelphia, USA

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    You can also search for this editor in PubMed   Google Scholar

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Table of contents (14 chapters)

  1. Front Matter

    Pages I-XXXI
    Download chapter PDF

  2. Cardiovascular activity

    • H. Gerhard Vogel, Wolfgang H. Vogel
    Pages 1-149

  3. Activity on blood constituents

    • H. Gerhard Vogel, Wolfgang H. Vogel
    Pages 150-167

  4. Renal activity

    • H. Gerhard Vogel, Wolfgang H. Vogel
    Pages 168-182

  5. Respiratory activity

    • H. Gerhard Vogel, Wolfgang H. Vogel
    Pages 183-203

  6. Psychotropic and neurotropic activity

    • H. Gerhard Vogel, Wolfgang H. Vogel
    Pages 204-316

  7. Drug effects on learning and memory

    • H. Gerhard Vogel, Wolfgang H. Vogel
    Pages 317-349

  8. Effects on peripheral nerve function

    • H. Gerhard Vogel, Wolfgang H. Vogel
    Pages 350-359

  9. Analgesic, anti-inflammatory, and antipyretic activity

    • H. Gerhard Vogel, Wolfgang H. Vogel
    Pages 360-420

  10. Anti-arthrotic and immunmodulatory activity

    • H. Gerhard Vogel, Wolfgang H. Vogel
    Pages 421-460

  11. Activity on the gastrointestinal tract

    • H. Gerhard Vogel, Wolfgang H. Vogel
    Pages 461-534

  12. Antidiabetic activity

    • H. Gerhard Vogel, Wolfgang H. Vogel
    Pages 535-597

  13. Anti-atherosclerotic activity

    • H. Gerhard Vogel, Wolfgang H. Vogel
    Pages 598-623

  14. Endocrinology

    • H. Gerhard Vogel, Wolfgang H. Vogel
    Pages 624-725

  15. Guidelines for the care and use of laboratory animals

    • Andreas W. Herling, Jochen Maas, Karl Seeger
    Pages 726-740

  16. Back Matter

    Pages 741-759
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Keywords

About this book

This reference book contains a comprehensive selection of the most frequently used assays for reliably detecting pharmacological effects of potential drugs, including tests for cardiovascular, analgesic, psychotropic, metabolic, endocrine, respiratory, renal, and immunomodulatory activities. Each of the over 700 assays comprises a detailed protocol with the purpose and rationale of the method, a description of the experimental procedure, a critical assessment of the results and their pharmacological and clinical relevance, and pertinent references. Identification of specific tests is facilitated by the enclosed CD-ROM which allows for a quick and full text research.
An appendix with guidelines and legal regulations for animal experiments in various countries will help to plan these experiments properly in accordance with the welfare of laboratory animals.

Editors and Affiliations

  • Johann Wolfgang Goethe Universität Frankfurt, Frankfurt am Main, Germany

    H. Gerhard Vogel

  • Philipps Universität Marburg, Marburg, Germany

    H. Gerhard Vogel

  • Department of Pharmacology Jefferson Medical College, Thomas Jefferson University, Philadelphia, USA

    Wolfgang H. Vogel

Bibliographic Information

  • Book Title: Drug Discovery and Evaluation

  • Book Subtitle: Pharmacological Assays

  • Editors: H. Gerhard Vogel, Wolfgang H. Vogel

  • DOI: https://doi.org/10.1007/978-3-662-03333-3

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1997

  • eBook ISBN: 978-3-662-03333-3Published: 17 April 2013

  • Edition Number: 1

  • Number of Pages: XXXI, 759

  • Topics: Pharmacology/Toxicology, Pharmacy, Biochemistry, general

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