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Susceptibility Factors Relevant for the Association Between Long-Term Air Pollution Exposure and Incident Asthma

  • Susceptibility Factors in Environmental Health (B Ritz, Section Editor)
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Abstract

In this review, we identified 15 studies in children and 10 studies in adults that assessed the association between long-term exposure to air pollution and incident asthma and that conducted stratified analyses to explore potential susceptibility factors. Overall, adult never-/former smokers seem to be at higher risk of incident asthma due to air pollution. Children without atopy and children from low socioeconomic status families also seem to be at higher risk of incident asthma due to air pollution. While interaction between air pollution and genes involved in the response to oxidative stress pathways have been explored, results are somewhat inconsistent and in need of replication. To evaluate interactions, large sample sizes are necessary, and much more research, including data pooling from existing studies, is needed to further explore susceptibility factors for asthma incidence due to long-term air pollution exposure.

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Acknowledgments

SESAP: ANSES EST-2012-166.

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Author notes

  1. Bénédicte Jacquemin

    Present address: CREAL-Centre for Research in Environmental Epidemiology Parc de Recerca Biomèdica de Barcelona, Doctor Aiguader, 88, 08003, Barcelona, Spain

Authors and Affiliations

  1. INSERM, U1168, VIMA: Aging and chronic diseases. Epidemiological and Public health approaches, F-94807, Villejuif, France

    Emilie Burte, Rachel Nadif & Bénédicte Jacquemin

  2. Versailles St-Quentin-en-Yvelines University, UMR-S 1168, 78180, Montigny le Bretonneux, France

    Emilie Burte, Rachel Nadif & Bénédicte Jacquemin

  3. Pompeu Fabra University (UPF), Barcelona, Spain

    Bénédicte Jacquemin

  4. CIBER Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain

    Bénédicte Jacquemin

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Burte, E., Nadif, R. & Jacquemin, B. Susceptibility Factors Relevant for the Association Between Long-Term Air Pollution Exposure and Incident Asthma. Curr Envir Health Rpt 3, 23–39 (2016). https://doi.org/10.1007/s40572-016-0084-1

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