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Report (2017) of the International Registry on Hand and Composite Tissue Allotransplantation (IRHCTT)

  • Vascularized Composite Allografts (L Cendales and R Barth, Section Editors)
  • Published:
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Abstract

Purpose of Review

Analysis of all upper extremity (UET) and face allotransplantations (FT) reported to the International Registry on Hand and Composite Tissue Transplantation (IRHCTT) by May 2017.

Recent Findings

The IRHCTT includes 66 cases of UET (18 unilateral and 38 bilateral) and 30 of FT. Acute and chronic rejections were reported in the presence of immunosuppression. Complications similar to those reported in solid organ transplantation occurred. UET patient survival was 96.7% at 1, 5, and 10 years after transplantation; graft survival was 90.4% at 1 year and 86.6% at 5 and 10 years. FT patient survival was 96.6% at 1 year and 96.2% at 5 years; graft survival was 96.6% at 1 and 5 years. The majority of UET and FT recipients were satisfied of their graft.

Summary

UET and FT are complex procedures requiring long-life immunosuppression; their success requires the patients’ careful selection, through evaluation, follow-up and compliance to the immunosuppression.

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Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Author information

Authors and Affiliations

  1. Department of Transplantation, Hopital Edouard Herriot, 5, place d’Arsonval, 69437, Lyon, France

    Palmina Petruzzo & Jean Michel Dubernard

  2. Department of Surgery, University of Cagliari, Cagliari, Italy

    Palmina Petruzzo

  3. Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy

    Claudia Sardu

  4. Italian Institute of Hand Surgery, Monza, Italy

    Marco Lanzetta

Authors
  1. Palmina Petruzzo
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  2. Claudia Sardu
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  3. Marco Lanzetta
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  4. Jean Michel Dubernard
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Corresponding author

Correspondence to Palmina Petruzzo.

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Conflict of Interest

P.P., C.S., M.L., and J.M.D. declare no conflict of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

Additional information

This article is part of the Topical Collection on Vascularized Composite Allografts

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Petruzzo, P., Sardu, C., Lanzetta, M. et al. Report (2017) of the International Registry on Hand and Composite Tissue Allotransplantation (IRHCTT). Curr Transpl Rep 4, 294–303 (2017). https://doi.org/10.1007/s40472-017-0168-3

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  • DOI: https://doi.org/10.1007/s40472-017-0168-3

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