Skip to main content

Advertisement

SpringerLink
Log in

Oral pH in gastroesophageal reflux disease

  • Original Article
  • Published:
Indian Journal of Gastroenterology Aims and scope Submit manuscript

Abstract

Aims and Objectives

The aim of this study is to compare surface pH in various parts of the oral cavity between patients with gastroesophageal reflux disease (GERD) and healthy controls.

Methods

Using a flat pH meter sensor, fixed electrode pen type digital pH meter, oral pH levels were assessed at different mucosal sites among 34 GERD patients and 32 healthy controls. Salivary flow rates and buffering capacity were also assessed in them. A thorough oral examination was performed to screen for any oral and dental changes.

Result

A significantly lower pH of 6.65 ± 0.13 (mean ± SD) was found in the GERD group compared to control group 7.23 ± 0.12 (p < 0.05). Least pH was found in the floor of the mouth 6.594 ± 0.17 and highest in the lower labial mucosa among the GERD patients. Salivary flow rate and buffering capacity were low in these patients. Significant changes were noticed in the hard and soft tissues of the oral cavity among the GERD group.

Conclusion

Oral mucosal pH is altered in GERD patients and may contribute to effects on the oral cavity.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Deschner WK, Benjamin SB. Extraesophageal manifestations of gastroesophageal reflux disease. Am J Gastroenterol. 1989;84:1–5.

    CAS  PubMed  Google Scholar 

  2. Cazzonatto H Jr, Bernasconi GCR, Pedrazzolli JR. Gastroesophageal reflux and oral lesions: is the acid that bad? Gastroenterol Endosc Dig. 2003;22:42–6.

  3. Myklebust S, Espelid I, Svalestad S, Tveit AB. Dental health behavior, gastroesophageal disorders and dietary habits among Norwegian recruits in 1990 and 1999. Acta Odontol Scand. 2003;61:100–4.

    Article  PubMed  Google Scholar 

  4. Barron RP, Carmichael RP, Marcon MA, Sàndor GK. Dental erosion in gastroesophageal reflux disease. J Can Dent Assoc. 2003;69:84–9.

    PubMed  Google Scholar 

  5. Armstrong D, Bennett JR, Blum AL, et al. The endoscopic assessment of esophagitis: a progress report on observer agreement. Gastroenterology. 1996;111:85–92.

    Article  CAS  PubMed  Google Scholar 

  6. Snaith RP. The hospital anxiety and depression scale. Health Qual Life Outcomes. 2003;1:29.

  7. Eccles JD, Jenkins WG. Dental erosion and diet. J Dent. 1974;2:153–9.

    Article  CAS  PubMed  Google Scholar 

  8. Kitasako Y, Burrow MF, Stacey M, Huq L, Reynolds EC, Tagami J. Comparative analysis of three commercial saliva testing kits with a standard saliva buffering test. Aust Dent J. 2008;53:140–4.

    Article  CAS  PubMed  Google Scholar 

  9. Kumar S, Sharma S, Norboo T, et al. Population based study to assess prevalence and risk factors of gastroesophageal reflux disease in a high altitude area. Indian J Gastroenterol. 2011;30:135–43.

    Article  CAS  PubMed  Google Scholar 

  10. Eisen GM, Sandler RS, Murray S, Gottfried M. The relationship between gastroesophageal reflux disease and its complications with Barrett’s esophagus. Am J Gastroenterol. 1997;92:27–31.

    CAS  PubMed  Google Scholar 

  11. Bansal A, Kahrilas PJ. Treatment of GERD complications (Barrett’s, peptic stricture) and extra-oesophageal syndromes. Best Pract Res Clin Gastroenterol. 2010;24:961–8.

    Article  PubMed  PubMed Central  Google Scholar 

  12. Corrêa MC, Lerco MM, Cunha Mde L, Henry MA. Salivary parameters and teeth erosions in patients with gastroesophageal reflux disease. Arq Gastroenterol. 2012;49:214–8.

    Article  PubMed  Google Scholar 

  13. Mota LAA, Santos ACO, Melo BC Jr, Travassos RO, Melo MSI. Videolaringoscopiae atividade da pepsina na saliva em voluntários com sintomas sugestivos de refluxo laringofaríngeo. Arq Int Otorrinolaringol. 2008;12:89–94.

  14. Eckley CA, Costa HO. Estudo comparativo do pH e do volume salivar em indivíduos com laringofaringite crônica por doença do refluxo gastroesofágico antes e após tratamento. Rev Bras Otorrinolaringol. 2006;72:55–60.

    Article  Google Scholar 

  15. Aframian DJ, Ofir M, Benoliel R. Comparison of oral mucosal pH values in bulimia nervosa, GERD, BMS patients and healthy population. Oral Dis. 2010;16:807–11.

    Article  CAS  PubMed  Google Scholar 

  16. Pace F, Pallotta S, Tonini M, Vakil N, Bianchi PG. Systematic review: gastro-oesophageal reflux disease and dental lesions. Aliment Pharmacol Ther. 2008;27:1179–86.

    Article  CAS  PubMed  Google Scholar 

  17. Munoz JV, Herreros B, Sanchiz V, et al. Dental and periodontal lesions in patients with gastro-oesophageal reflux disease. Dig Liver Dis. 2003;35:461–7.

    Article  CAS  PubMed  Google Scholar 

  18. Ersin NK, Onçağ O, Tümgör G, Aydoğdu S, Hilmioğlu S. Oral and dental manifestations of gastroesophageal reflux disease in children: a preliminary study. Pediatr Dent. 2006;28:279–84.

    PubMed  Google Scholar 

  19. Campisi G, Di Fede O, Roccia P, Di Nicola F, Falaschini S, Lo ML. Saliva: its value as biological matrix and current methods of sampling. Eur J Inflamm. 2006;4:11–9.

    Google Scholar 

  20. Edgar WM. Saliva and dental health, clinical implications of saliva: report of a consensus meeting. Br Dent J. 1990;169:96–8.

    Article  CAS  PubMed  Google Scholar 

  21. Sun A, Wu KM, Wang YP, Lin HP, Chen HM, Chiang CP. Burning mouth syndrome: a review and update. J Oral Pathol Med. 2013;42:649–55.

    Article  PubMed  Google Scholar 

  22. Di Fede O, Di Liberto C, Occhipinti G, et al. Oral manifestations in patients with gastro-oesophageal reflux disease: a single-center case–control study. J Oral Pathol Med. 2008;37:336–40.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Oral Medicine and Radiology, M S Ramaiah Dental College and Hospital, MSRIT Post, M S R Nagar, Bengaluru, 560 054, India

    S. Sujatha, Yashoda Devi, N. Rakesh & Shivani Sharma

  2. Department of Gastroenterology, M S Ramaiah Dental College and Hospital, MSRIT Post, M S R Nagar, Bengaluru, 560 054, India

    Umesh Jalihal

  3. Department of Oral Medicine and Radiology, Shree Bankey Bihari Dental College and Research Centre, Ahead Masuri Canal, NH-24, Masuri, Kakrana, 201 302, India

    Pallavi Chauhan

Authors
  1. S. Sujatha
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Umesh Jalihal
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Yashoda Devi
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. N. Rakesh
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Pallavi Chauhan
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Shivani Sharma
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to S. Sujatha.

Ethics declarations

Conflict of interest

SS, UJ, YD, NR, PC, and SS declare that they have no competing interests.

Ethics statement

The study was performed in a manner to conform to the Helsinki declaration of 1975, as revised in 2000 and 2008 concerning human and animal rights and that the authors followed the policy concerning the informed consent as shown on Springer.com.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Sujatha, S., Jalihal, U., Devi, Y. et al. Oral pH in gastroesophageal reflux disease. Indian J Gastroenterol 35, 186–189 (2016). https://doi.org/10.1007/s12664-016-0659-7

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12664-016-0659-7

Keywords

Search

Navigation