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Current evidence-based opinions in the management of adenocarcionoma of the rectum

  • Review Article
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Abstract

The management of rectal cancer has drastically evolved over the past two decades as a result of implementation of circular stapling devices and the introduction of neoadjuvant chemoradiation. In spite of current aggressive multimodality treatments, the recurrence rate remains unacceptably high and the expected 5-year survival in patients who develop recurrent disease is dismal. The management of rectal cancer must involve a multidisciplinary approach. An understanding of the biology of rectal tumours may allow for selection of patients who may have an aggressive phenotype allowing for alterations in the operative and neoadjuvant planning. Efforts to improve local control and survival in rectal cancer are the focus of multiple current clinical and preclinical research efforts. Preoperative chemoradiation for and surgical management of rectal cancer, including the laparoscopic approach are areas of dynamic progression. In the present report, we review the current evidence in the new strategies pertaining to the multimodality approach in the management of rectal cancer.

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Author information

Authors and Affiliations

  1. Division of Surgery, University of Texas Southwestern Medical Center/Dallas VA Medical Center, Dallas, USA

    Sergio Huerta & Bryce Murray

  2. Colorectal Surgery, University of Texas Southwestern Medical Center/Dallas VA Medical Center, Dallas, USA

    Craig Olson

  3. Medical Oncology, University of Texas Southwestern Medical Center/Dallas VA Medical Center, Dallas, USA

    Prapti Patel

  4. Surgical Oncology, University of Texas Southwestern Medical Center/Dallas VA Medical Center, Dallas, USA

    Thomas Anthony

Authors
  1. Sergio Huerta
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  2. Bryce Murray
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  3. Craig Olson
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  4. Prapti Patel
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  5. Thomas Anthony
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Correspondence to Sergio Huerta.

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Huerta, S., Murray, B., Olson, C. et al. Current evidence-based opinions in the management of adenocarcionoma of the rectum. Indian J Surg 71, 356–362 (2009). https://doi.org/10.1007/s12262-009-0094-4

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  • DOI: https://doi.org/10.1007/s12262-009-0094-4

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