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Recent advances in chemical proteomics: exploring the post-translational proteome

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Journal of Chemical Biology

Abstract

Identification and quantification of multiple proteins from complex mixtures is a central theme in post-genomic biology. Despite recent progress in high-throughput proteomics, proteomic analysis of post-translationally modified (PTM) proteins remains particularly challenging. This mini-review introduces the emerging field of chemical proteomics and reviews recent advances in chemical proteomic technology that are offering striking new insights into the functional biology of post-translational modification.

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The author thanks the Biotechnology and Biological Sciences Research Council (BBSRC), UK for the award of a David Phillips Research Fellowship.

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    Edward W. Tate

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Tate, E.W. Recent advances in chemical proteomics: exploring the post-translational proteome. J Chem Biol 1, 17–26 (2008). https://doi.org/10.1007/s12154-008-0002-6

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