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Cogan’s Syndrome: Clinical Presentations and Update on Treatment

  • Autoimmunity (T Tarrant, Section Editor)
  • Published:
Current Allergy and Asthma Reports Aims and scope Submit manuscript

Abstract

Purpose of Review

Cogan’s syndrome (CS) is a rare systemic vasculitis that can severely affect vision and hearing, which may also have significant systemic effects. Early recognition of this autoimmune disorder and intervention can minimize disabling and irreversible damage.

Recent Findings

This article will review the varying clinical presentations of CS and emerging information of systemic disease associated with CS. We will also review recently published promising treatment outcomes using immune modulating medications.

Summary

As our framework for recognizing the markers of CS and the associated systemic disorders expands, more effective guidelines and treatment options may emerge.

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References

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Authors and Affiliations

  1. Department of Ophthalmology, Saint Louis University Eye Institute, Saint Louis University School of Medicine, 1755 South Grand Blvd., St. Louis, MO, 63104, USA

    Gabriela Mabel Espinoza & Angela Prost Keller

  2. Department of Internal Medicine, Saint Louis University School of Medicine, 1402 South Grand Blvd. Doisy Hall 210, St. Louis, MO, 63104, USA

    Joseph Wheeler

  3. Rheumatology & Internal Medicine Associates, BJC Medical Group, 3023 N. Ballas Road, Suite 500D, St. Louis, MO, 63131, USA

    Katherine K. Temprano

Authors
  1. Gabriela Mabel Espinoza
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  2. Joseph Wheeler
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  3. Katherine K. Temprano
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  4. Angela Prost Keller
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Corresponding author

Correspondence to Gabriela Mabel Espinoza.

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Espinoza, G.M., Wheeler, J., Temprano, K.K. et al. Cogan’s Syndrome: Clinical Presentations and Update on Treatment. Curr Allergy Asthma Rep 20, 46 (2020). https://doi.org/10.1007/s11882-020-00945-1

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