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Nutritional Deficiencies in Gastric Bypass Patients; Incidence, Time of Occurrence and Implications for Post-operative Surveillance

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Abstract

Background

Post-operative nutritional deficiencies are a common complication following bariatric surgery. The incidence and time of occurrence are not clear, and the efficacy of supplementation remains questionable. Clear guidelines for nutritional follow-up and counselling are needed.

Methods

Preoperative and post-operative deficiencies were determined in a group of 427 gastric bypass patients. The predictive value of preoperative laboratory findings for the development of post-operative deficiencies, the time of occurrence and the effect of supplementation of common deficiencies was studied.

Results

Most common preoperative deficiencies were of folic acid (21.3 %), vitamin D3 (17.5 %) and iron (21.8 %). Post-operative, a significant increase in the number of patients with anaemia and deficiencies of ferritin and vitamin B12 was found. Most deficiencies occur between 12 and 15 months post-operatively, but vitamin D3 deficiency occurs significantly earlier at 9.7 months. A preoperative iron, folic acid or ferritin deficiency results in a significant higher risk for developing a post-operative deficiency despite supplementation, and ferritin deficiency occurs significantly earlier in these patients. Oral treatment of post-operative vitamin B12 and vitamin D3 deficiencies was successful in more than 80 % of the patients in contrast to oral treatment of anaemia which was only successful in 62.5 % of the patients.

Conclusion

Our study emphasizes the importance of preoperative assessment and treatment of nutritional deficiencies in morbidly obese patients undergoing gastric bypass surgery. Despite limited efficacy, post-operative oral supplementation should be encouraged as it decreases the incidence of deficiencies.

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References

  1. Agha-Mohammadi S, Hurwitz DJ. Nutritional deficiency of post-bariatric surgery body contouring patients: what every plastic surgeon should know. Plast Reconstr Surg. 2008;122:604–13.

    Article  CAS  PubMed  Google Scholar 

  2. Blume CA, Boni CC, Casagrande DS, et al. Nutritional profile of patients before and after Roux-en-Y gastric bypass: 3-years follow-up. Obes Surg. 2012;22:1676–85.

    Article  PubMed  Google Scholar 

  3. Clements RH, Katasani VG, Palepu R, et al. Incidence of vitamin deficiency after laparoscopic Roux-en-Y gastric bypass in a university hospital setting. Am Surg. 2006;72:1196–202.

    PubMed  Google Scholar 

  4. Dalcanale L, Oliveira CP, Faintuch J, et al. Long-term nutritional outcome after gastric bypass. Obes Surg. 2010;20:181–7.

    Article  PubMed  Google Scholar 

  5. Donadelli SP, Junqueira-Franco MV, de Mattos Donadelli CA, et al. Daily vitamin supplementation and hypovitaminosis after obesity surgery. Nutrition. 2012;28:391–6.

    Article  CAS  PubMed  Google Scholar 

  6. Higa K, Ho T, Tercero F, et al. Laparoscopic Roux-en-Y gastric bypass: 10-year follow-up. Surg Obes Relat Dis. 2011;7:516–25.

    Article  PubMed  Google Scholar 

  7. Gasteyer C, Suter M, Gaillard RC, et al. Nutritional deficiencies after Roux-en-Y gastric bypass for morbid obesity often cannot be prevented by standard multivitamin supplementation. Am J Clin Nutr. 2008;87:1128–33.

    Google Scholar 

  8. Kaidar-Person O, Person B, Szomstein S, et al. Nutritional deficiencies in morbidly obese patients: a new form of malnutrition? Part A: vitamins. Obes Surg. 2008;18:870–6.

    Article  PubMed  Google Scholar 

  9. Flancbaum L, Belsley S, Drake V, et al. Preoperative nutritional status of patients undergoing Roux-en-Y gastric bypass for morbid obesity. J Gastrointest Surg. 2006;10:1033–7.

    Article  PubMed  Google Scholar 

  10. Gastrointestinal surgery for severe obesity; National Institutes of Health consensus development conferende statement. Am J Clin Nutr. 1992;55:615S–619S.

  11. Shah M, Simha V, Garg A. Review: long-term impact of bariatric surgery on body weight, comorbidities, and nutritional status. J Clin Endocr Metab. 2006;91:4223–31.

    Article  CAS  PubMed  Google Scholar 

  12. Xanthakos SA. Nutritional deficiencies in obesity and after bariatric surgery. Pediatr Clin N Am. 2009;56:1105–21.

    Article  Google Scholar 

  13. Aasheim ET, Johnson LK, Hofsø D, et al. Vitamin status after gastric bypass and lifestyle intervention: a comparative prospective study. Surg Obes Relat Dis. 2012;8:169–75.

    Article  PubMed  Google Scholar 

  14. Coupaye M, Puchaux K, Bogard C, et al. Nutritional consequences of adjustable gastric banding and gastric bypass: a 1-year prospective study. Obes Surg. 2009;19:56–65.

    Article  PubMed  Google Scholar 

  15. Moize V, Geliebter A, Gluck ME, et al. Obese patients have inadequate protein intake related to protein intolerance up to 1 year following Roux-en-Y gastric bypass. Obes Surg. 2003;13:23–8.

    Article  PubMed  Google Scholar 

  16. Ponsky TA, Brody F, Pucci E. Alterations in gastrointestinal physiology after Roux-en-y gastric bypass. J Am Coll Surg. 2005;201:125–31.

    Article  PubMed  Google Scholar 

  17. Vargas-Ruiz AG, Hernandez-Rivera G, Herrera MF. Prevalence of iron, folate and vitamin B12 deficient anemia after laparoscopic Roux-en-Y gastric bypass. Obes Surg. 2008;18:288–93.

    Article  PubMed  Google Scholar 

  18. Colossi FG, Casagrande DS, Chatkin R, et al. Need for multivitamin use in the postoperative period of gastric bypass. Obes Surg. 2008;18:187–91.

    Article  PubMed  Google Scholar 

  19. Novais PF, Resera Jr I, Leite CV, et al. Food intake in women two years or more after bariatric surgery meets adequate intake requirements. Nutr Res. 2012;32:335–41.

    Article  CAS  PubMed  Google Scholar 

  20. Aarts EO, Dogan K, Betzel et al. A double-blind prospective randomized controlled trial comparing multivitamin supplements after roux-en-Y gastric bypass in morbidly obese patients: vital study. On IFSO, 18th cong. 2nd session (Aug. 30, 2013).

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The authors declare that they have no conflict of interest

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Correspondence to Eva S. J. van der Beek.

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van der Beek, E.S.J., Monpellier, V.M., Eland, I. et al. Nutritional Deficiencies in Gastric Bypass Patients; Incidence, Time of Occurrence and Implications for Post-operative Surveillance. OBES SURG 25, 818–823 (2015). https://doi.org/10.1007/s11695-014-1456-y

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