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Uveal melanoma: evaluation of extrascleral extension using thin-section MR of the eye with surface coils

  • Magnetic Resonance Imaging
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Abstract

Purpose

This study was done to evaluate the role of high-resolution magnetic resonance (MR) imaging with special surface coils in selecting the correct therapeutic approach (eye enucleation or follow-up) in patients with suspected extrascleral extension of uveal melanoma.

Materials and methods

This prospective study involved 12 patients with suspected extrascleral extension of uveal melanoma on orbital ultrasonography. All patients were studied with thin-section MR imaging of the eye using surface coils.

Results

High-resolution MR imaging of the eye excluded extrascleral extension of disease in 8/12 patients: in 4/8 cases it revealed vascular ectasia and in the other 4/8 cases the linear hypointensity of the sclera was unbroken. Seven of these eight patients were followed up by ultrasound, which showed stability of melanoma for at least 2 years, while the last patient underwent enucleation, and the histological examination confirmed the MR diagnosis. In 4/12 patients, high-resolution MR suggested a diagnosis of extrascleral extension of melanoma, which was confirmed at histological examination after enucleation.

Conclusion

High-resolution MR imaging of the eye with surface coils allowed us to evaluate extrascleral extension of uveal melanoma and choose the correct therapeutic approach, avoiding unnecessary enucleation in 7/12 patients.

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Conflict of interest

Tommaso Tartaglione, Monica Maria Pagliara, Mariacarmela Sciandra, Carmela Grazia Caputo, Rosalinda Calandrelli, Gina Fabrizi, Simona Gaudino, Maria Antonietta Blasi, Cesare Colosimo declare no conflict of interest.

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Authors and Affiliations

  1. Dipartimento di Scienze Radiologiche, Istituto di Radiologia, Policlinico Agostino Gemelli, UCSC, Rome, Italy

    Tommaso Tartaglione, Mariacarmela Sciandra, Rosalinda Calandrelli, Gina Fabrizi, Simona Gaudino & Cesare Colosimo

  2. Dipartimento di Scienze Chirurgiche per le Patologie della Testa e del Collo, Istituto di Oftalmologia, Policlinico Agostino Gemelli, UCSC, Rome, Italy

    Monica Maria Pagliara, Carmela Grazia Caputo & Maria Antonietta Blasi

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  1. Tommaso Tartaglione
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  2. Monica Maria Pagliara
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Correspondence to Tommaso Tartaglione.

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Tartaglione, T., Pagliara, M.M., Sciandra, M. et al. Uveal melanoma: evaluation of extrascleral extension using thin-section MR of the eye with surface coils. Radiol med 119, 775–783 (2014). https://doi.org/10.1007/s11547-014-0388-x

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