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Degradation potential of ofloxacin and its resulting transformation products during Fenton oxidation process

  • Article
  • Chemical Engineering
  • Published:
Chinese Science Bulletin

Abstract

The degradation of ofloxacin (OFX) in the aqueous solution by Fenton oxidation process was investigated in the present study. The optimum operating conditions for the degradation of OFX in our system was determined. More importantly, the degradation pathways on a basis of the identification of transformation products during the degradation of OFX were proposed, which revealed that the initial degradation step could be associated with the decarboxylation at the quinolone moiety. Moreover, the detachment of the F element during the Fenton oxidation process has also been detected. Since the carboxylic group within OFX has been considered as an important bridge for binding quinolones with the DNA gyrase target, the decarboxylation process would offer insights into the reduction of antibacterial potentials.

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Acknowledgments

This work was supported by the Foundation and Advanced Technology Research Program of Henan Province (102300410098, 0611020900, 102300410193, and 122300410286), the Innovation Scientists and Technicians Troop Construction Projects of Henan Province, and the Plan for Scientific Innovation Talent of Henan Province.

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Authors and Affiliations

  1. School of Environment, Henan Normal University, Xinxiang, 453007, China

    Yunqing Pi, Jinglan Feng, Mengke Song & Jianhui Sun

  2. Key Laboratory for Yellow River and Huaihe River Water Environmental and Pollution Control, Ministry of Education, Xinxiang, 453007, China

    Yunqing Pi, Jinglan Feng, Mengke Song & Jianhui Sun

  3. Henan Key Laboratory for Environmental Pollution Control, Xinxiang, 453007, China

    Yunqing Pi, Jinglan Feng, Mengke Song & Jianhui Sun

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  1. Yunqing Pi
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  2. Jinglan Feng
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  3. Mengke Song
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  4. Jianhui Sun
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Correspondence to Jinglan Feng or Jianhui Sun.

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Pi, Y., Feng, J., Song, M. et al. Degradation potential of ofloxacin and its resulting transformation products during Fenton oxidation process. Chin. Sci. Bull. 59, 2618–2624 (2014). https://doi.org/10.1007/s11434-014-0293-7

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  • DOI: https://doi.org/10.1007/s11434-014-0293-7

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