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Bray–Liebhafsky oscillatory reaction as the matrix system for the kinetic determination of microquantities of alizarin and purpurin

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Abstract

Two hydroxyanthraquinones, alizarin and purpurin, that have been used throughout history as a natural pigment, were extracted from roots of Rubia tinctorum from Serbia. As substances with important chemical activities and, therefore, with wide applications (for example in dyeing textile fabrics as well as in pharmacy because of their anti-inflammatory, anti-cancer, antiviral, antimicrobial and antioxidant activities, etc.) they were analyzed in the kinetically very sensitive Bray–Liebhafsky (BL) oscillatory reaction. However, although they are both, hydroxyanthraquinones it is shown that their interactions with BL nonlinear reaction system differ significantly. Consequently, two different reactions were used to explain the mechanism of their chemical activities. The numerical simulations based on a standard model of the BL oscillatory reaction together with proposed reactions due to alizarin/purpurin interactions with a matrix are correlated with experimental investigations. Moreover, it is shown that very small amounts of alizarin and purpurin (from about 1 × 10–7 M) produce the response of the BL matrix such that micro-quantitative analysis based on the BL oscillatory reaction can be successfully performed in this reaction system. The linear response of the BL matrix on the presence of alizarin and purpurin (necessary for microquantitative determination) is analyzed as a function of two concentration sensitive parameters: pre-oscillatory period τ1 and potential shift after perturbation ΔE.

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Acknowledgements

This work was partially supported by the Ministry of Education, Science and Technological Development of Republic of Serbia (Grant Numbers OI 172015 and III 45001, and Contract numbers 451-03-68/2020-14/200026, 451-03-68/2020-14/200111 and 451-03-68/2020-14/200146). We are grateful to Prof. N. Pejić for fruitful discussion.

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Authors and Affiliations

  1. Faculty of Physical Chemistry, University of Belgrade, Studentski trg 12-16, 11000, Belgrade, Serbia

    Jelena Maksimović, Aleksandra Đerić, Slobodan Anić & Ljiljana Kolar-Anić

  2. Department of Catalysis and Chemical Engineering, Institute of Chemistry, Technology and Metallurgy, University of Belgrade, Njegoševa 12, 11000, Belgrade, Serbia

    Željko Čupić & Slobodan Anić

  3. Department of Pharmacy, Faculty of Medical Sciences, University of Kragujevac, Svetozara Markovića 69, 34000, Kragujevac, Serbia

    Nedeljko Manojlović

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  1. Jelena Maksimović
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  2. Željko Čupić
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Correspondence to Željko Čupić.

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Maksimović, J., Čupić, Ž., Manojlović, N. et al. Bray–Liebhafsky oscillatory reaction as the matrix system for the kinetic determination of microquantities of alizarin and purpurin. Reac Kinet Mech Cat 130, 655–668 (2020). https://doi.org/10.1007/s11144-020-01798-5

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