Abstract
This case report discusses a patient with sickle cell disease who presented with fungemia from Pichia anomala (teleomorph: Candida pelliculosa). The organism was identified as P. anomala by MALDI-TOF VITEK mass spectrometry and VITEK 2 yeast identification card. Pichia anomala should be considered in sickle cell patients with recurrent fungemia.
References
Aragao PA, Oshiro IC, Manrique EI, Gomes CC, Matsuo LL, Leone C, et al. Pichia anomala outbreak in a nursery: exogenous source? Pediatr Infect Dis J. 2001;20(9):843–8.
Bakir M, Cerikcioglu N, Tirtir A, Berrak S, Ozek E, Canpolat C. Pichia anomala fungaemia in immunocompromised children. Mycoses. 2004;47(5–6):231–5. doi:10.1111/j.1439-0507.2004.00962.x.
Chakrabarti A, Singh K, Narang A, Singhi S, Batra R, Rao KL, et al. Outbreak of Pichia anomala infection in the pediatric service of a tertiary-care center in Northern India. J Clin Microbiol. 2001;39(5):1702–6. doi:10.1128/JCM.39.5.1702-1706.2001.
Chitasombat MN, Kofteridis DP, Jiang Y, Tarrand J, Lewis RE, Kontoyiannis DP. Rare opportunistic (non-Candida, non-Cryptococcus) yeast bloodstream infections in patients with cancer. J Infect. 2012;64(1):68–75. doi:10.1016/j.jinf.2011.11.002.
Klein AS, Tortora GT, Malowitz R, Greene WH. Hansenula anomala: a new fungal pathogen. Two case reports and a review of the literature. Arch Intern Med. 1988;148(5):1210–3.
Goss G, Grigg A, Rathbone P, Slavin M. Hansenula anomala infection after bone marrow transplantation. Bone Marrow Transplant. 1994;14(6):995–7.
Haron E, Anaissie E, Dumphy F, McCredie K, Fainstein V. Hansenula anomala fungemia. Rev Infect Dis. 1988;10(6):1182–6.
Choi SW, Lee TJ, Kim MK, Lee M, Jung JH. A case of fungal arthritis caused by Hansenula anomala. Clin Orthop Surg. 2010;2(1):59–62. doi:10.4055/cios.2010.2.1.59.
Park KA, Ahn K, Chung ES, Chung TY. Pichia anomala fungal keratitis. Cornea. 2008;27(5):619–20. doi:10.1097/ICO.0b013e318166c442.
Qadri SM, Al Dayel F, Strampfer MJ, Cunha BA. Urinary tract infection caused by Hansenula anomala. Mycopathologia. 1988;104(2):99–101.
Hanada K, Miyokawa N, Sano A, Igarashi S, Yoshida A. Fungal dacryocystitis with cacosmia after penetrating keratoplasty–taxonomy and identification of pathogenic fungi based on DNA sequence analysis. Nippon Ganka Gakkai zasshi. 2012;116(12):1144–9.
Krcmery V, Kisac P, Liskova A. Voriconazole and posaconazole resistant Candida pelliculosa fungemia after cardiac surgery. Pediatr Infect Dis J. 2009;28(1):75–6. doi:10.1097/INF.0b013e31818edde1.
Neumeister B, Rockemann M, Marre R. Fungaemia due to Candida pelliculosa in a case of acute pancreatitis. Mycoses. 1992;35(11–12):309–10.
da Matta VL, de Melhem MSC, Colombo AL, Moretti ML, Rodero L, Duboc de Almeida GM, et al. Antifungal drug susceptibility profile of Pichia anomala isolates from patients presenting with nosocomial fungemia. Antimicrob Agents Chemother. 2007;51(4):1573–6.
Kurtzman CP. Phylogeny of the ascomycetous yeasts and the renaming of Pichia anomala to Wickerhamomyces anomalus. Antonie Van Leeuwenhoek. 2011;99(1):13–23. doi:10.1007/s10482-010-9505-6.
Novak EK, Vitez I. Mycological investigations on clinical materials. II. Description of new yeasts. Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene 1 Abt Medizinisch-hygienische Bakteriologie, Virusforschung und Parasitologie Originale. 1964; 193(1):127–33.
Acknowledgments
The authors received financial support from CSK—NIH/NCRR KL2 TR000455.
Conflict of interest
None.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Chan, A.W., Cartwright, E.J., Reddy, S.C. et al. Pichia anomala (Candida pelliculosa) Fungemia in a Patient with Sickle Cell Disease. Mycopathologia 176, 273–277 (2013). https://doi.org/10.1007/s11046-013-9677-5
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11046-013-9677-5