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Physical and chemical characteristics of Maytenus rigida in different particle sizes using SEM/EDS, TG/DTA and pyrolysis GC–MS

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Abstract

Thermoanalytical techniques have been widely applied in the characterization of herbal medicines, providing data about the herbal products quality. The objective of this work was to use analytical techniques for the Maytenus rigida powder in different particle sizes characterization. The techniques used were scanning electron microscopy (SEM) with energy-dispersive spectroscopy, differential thermal analysis (DTA), Thermogravimetry (TG), using the model of Ozawa to evaluate the kinetic parameters and gas chromatography coupled to pyrolysis/mass spectrometry (PYR-GC/MS). Different particle morphologies and size were verified by SEM. The thermoanalytical techniques (TG and DTA) showed physical and chemical processes occurred. Different degradation profiles curves were obtained when the samples were exposed to the atmosphere of nitrogen and synthetic air. Kinetic data showed different activation energy values and the same reaction order to the studied samples. Through Ozawa kinetic parameters, it was possible to observe granulometries distinctions to the herbal medicine powder batches. Pyrolysis allowed to correlate TG decomposition data with the identification of its degradation products and showed two similar compounds among the samples at lower temperatures (250 °C) and at higher temperatures (600 °C). The fingerprint of the degradation components by PYR-GC–MS and the other analytical tools has been utilized as an alternative to the quality control of herbal medicine evaluation. E a obtained by dynamic TG in air synthetic atmosphere was the parameter which better differentiate the samples.

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Acknowledgements

The authors would like to thank the Emater for support in the herbal collection steps.

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Authors and Affiliations

  1. Department of Pharmaceutical Sciences, Postgraduate Program in Pharmaceutical Sciences, Federal University of Pernambuco, University City, Artur de Sá Avenue, Recife, 50740-521, Brazil

    Lidiane Pinto Correia, Karla Monik Alves da Silva, Fernando José de Lima Ramos Júnior, Fábio Santos de Souza & Rui Oliveira Macêdo

  2. Laboratory of Development and Assays of Drugs, State University of Paraíba, R. Baraúnas, 351, University City, Campina Grande, Paraíba, 58429-500, Brazil

    Lidiane Pinto Correia, Cleildo Pereira de Santana & Ana Cláudia Dantas de Medeiros

  3. Department of Pharmacy, State University of Paraíba, R. Baraúnas, 351, University City, Campina Grande, Paraíba, 58429-500, Brazil

    Lidiane Pinto Correia, Rosemary Sousa Cunha Lima & Ana Cláudia Dantas de Medeiros

  4. Unified Laboratories of Pharmaceutical Development and Assays, Department of Pharmaceutical Sciences, Federal University of Paraíba, Campus I, University City, João Pessoa, Paraíba, 58059-970, Brazil

    Fábio Santos de Souza & Rui Oliveira Macêdo

Authors
  1. Lidiane Pinto Correia
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  2. Cleildo Pereira de Santana
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  3. Karla Monik Alves da Silva
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  4. Fernando José de Lima Ramos Júnior
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  5. Rosemary Sousa Cunha Lima
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  6. Fábio Santos de Souza
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  7. Ana Cláudia Dantas de Medeiros
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  8. Rui Oliveira Macêdo
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Correspondence to Ana Cláudia Dantas de Medeiros.

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Correia, L.P., de Santana, C.P., da Silva, K.M.A. et al. Physical and chemical characteristics of Maytenus rigida in different particle sizes using SEM/EDS, TG/DTA and pyrolysis GC–MS. J Therm Anal Calorim 131, 743–752 (2018). https://doi.org/10.1007/s10973-016-5999-0

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  • DOI: https://doi.org/10.1007/s10973-016-5999-0

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