Skip to main content
Log in

Continuous noninvasive arterial blood pressure monitoring using the vascular unloading technology during complex gastrointestinal endoscopy: a prospective observational study

  • Original Research
  • Published:
Journal of Clinical Monitoring and Computing Aims and scope Submit manuscript

Abstract

The innovative vascular unloading technology (VUT) allows continuous noninvasive arterial blood pressure (AP) monitoring. We aimed to investigate whether the VUT enables AP changes to be detected earlier compared with intermittent AP monitoring in patients undergoing gastrointestinal endoscopy. In this prospective observational study, we recorded continuous AP measurements with the VUT (CNAP system; CNSystems Medizintechnik AG, Graz, Austria) and intermittent AP measurements with upper arm cuff oscillometry in 90 patients undergoing complex gastrointestinal endoscopy (Department of Interventional Endoscopy at the University Medical Center Hamburg-Eppendorf, Hamburg, Germany). A “hypotensive phase” was defined as a time period of at least 30 s during which ≥ 50% of the VUT-AP values were in a predefined range of hypotension, i.e., AP value a) ≥ 10% below the last oscillometric value and b) ≤ 65 mmHg for mean AP or ≤ 90 mmHg for systolic AP. In the 5-min-interval between two oscillometric measurements, one or more hypotensive phases were detected in 26 patients (29%) for mean AP and in 27 patients (30%) for systolic AP. Hypotensive phases had a mean duration of 195 ± 99 s for mean AP and 197 ± 97 s for systolic AP with a mean procedure duration of 36 (± 21) min. Continuous noninvasive AP monitoring using the VUT enables hypotensive phases to be detected earlier compared with intermittent AP monitoring during complex gastrointestinal endoscopy. These hypotensive phases may be missed or only belatedly recognized with intermittent AP monitoring. Continuous noninvasive AP measurement facilitates detecting hemodynamic instability more rapidly and therefore may improve patient safety.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. Bartels K, Esper SA, Thiele RH. Blood pressure monitoring for the anesthesiologist: a practical review. Anesth Analg. 2016;122:1866–79. https://doi.org/10.1213/ane.0000000000001340.

    Article  CAS  PubMed  Google Scholar 

  2. Saugel B, Dueck R, Wagner JY. Measurement of blood pressure. Best Pract Res Clin Anaesthesiol. 2014;28:309–22. https://doi.org/10.1016/j.bpa.2014.08.001.

    Article  PubMed  Google Scholar 

  3. Chung E, Chen G, Alexander B, Cannesson M. Non-invasive continuous blood pressure monitoring: a review of current applications. Front Med. 2013;7:91–101. https://doi.org/10.1007/s11684-013-0239-5.

    Article  PubMed  Google Scholar 

  4. Saugel B, Reuter DA. Are we ready for the age of non-invasive haemodynamic monitoring? Br J Anaesth. 2014;113:340–3. https://doi.org/10.1093/bja/aeu145.

    Article  CAS  PubMed  Google Scholar 

  5. Wagner JY, Saugel B. When should we adopt continuous noninvasive hemodynamic monitoring technologies into clinical routine? J Clin Monit Comput. 2015;29:1–3. https://doi.org/10.1007/s10877-014-9619-x.

    Article  PubMed  Google Scholar 

  6. Thiele RH. Cardiac bulldozers, backhoes, and blood pressure. Anesth Analg. 2015;121:1417–9. https://doi.org/10.1213/ane.0000000000000983.

    Article  PubMed  Google Scholar 

  7. Jeleazcov C, Krajinovic L, Munster T, et al. Precision and accuracy of a new device (CNAPTM) for continuous non-invasive arterial pressure monitoring: assessment during general anaesthesia. Br J Anaesth. 2010;105:264–72. https://doi.org/10.1093/bja/aeq143.

    Article  CAS  PubMed  Google Scholar 

  8. Ilies C, Bauer M, Berg P, et al. Investigation of the agreement of a continuous non-invasive arterial pressure device in comparison with invasive radial artery measurement. Br J Anaesth. 2012;108:202–10. https://doi.org/10.1093/bja/aer394.

    Article  CAS  PubMed  Google Scholar 

  9. Martina JR, Westerhof BE, van Goudoever J, et al. Noninvasive continuous arterial blood pressure monitoring with Nexfin(R). Anesthesiology. 2012;116:1092–103. https://doi.org/10.1097/ALN.0b013e31824f94ed.

    Article  CAS  PubMed  Google Scholar 

  10. Jagadeesh AM, Singh NG, Mahankali S. A comparison of a continuous noninvasive arterial pressure (CNAP) monitor with an invasive arterial blood pressure monitor in the cardiac surgical ICU. Ann Card Anaesth. 2012;15:180–4. https://doi.org/10.4103/0971-9784.97973.

    Article  CAS  PubMed  Google Scholar 

  11. Smolle KH, Schmid M, Prettenthaler H, Weger C. The accuracy of the CNAP(R) device compared with invasive radial artery measurements for providing continuous noninvasive arterial blood pressure readings at a medical intensive care unit: a method-comparison study. Anesth Analg. 2015;121:1508–16. https://doi.org/10.1213/ANE.0000000000000965.

    Article  PubMed  Google Scholar 

  12. Wagner JY, Negulescu I, Schofthaler M, et al. Continuous noninvasive arterial pressure measurement using the volume clamp method: an evaluation of the CNAP device in intensive care unit patients. J Clin Monit Comput. 2015;29:807–13. https://doi.org/10.1007/s10877-015-9670-2.

    Article  PubMed  Google Scholar 

  13. Ilies C, Kiskalt H, Siedenhans D, et al. Detection of hypotension during Caesarean section with continuous non-invasive arterial pressure device or intermittent oscillometric arterial pressure measurement. Br J Anaesth. 2012;109:413–9. https://doi.org/10.1093/bja/aes224.

    Article  CAS  PubMed  Google Scholar 

  14. Siebig S, Rockmann F, Sabel K, et al. Continuous non-invasive arterial pressure technique improves patient monitoring during interventional endoscopy. Int J Med Sci. 2009;6:37–42.

    Article  PubMed  PubMed Central  Google Scholar 

  15. Wagner JY, Prantner JS, Meidert AS, Hapfelmeier A, Schmid RM, Saugel B. Noninvasive continuous versus intermittent arterial pressure monitoring: evaluation of the vascular unloading technique (CNAP device) in the emergency department. Scand J Trauma Resusc Emerg Med. 2014;22:8. https://doi.org/10.1186/1757-7241-22-8.

    Article  PubMed  PubMed Central  Google Scholar 

  16. Sharma VK, Nguyen CC, Crowell MD, Lieberman DA, de Garmo P, Fleischer DE. A national study of cardiopulmonary unplanned events after GI endoscopy. Gastrointest Endosc. 2007;66:27–34. https://doi.org/10.1016/j.gie.2006.12.040.

    Article  PubMed  Google Scholar 

  17. Salmasi V, Maheshwari K, Yang D, et al. Relationship between intraoperative hypotension, defined by either reduction from baseline or absolute thresholds, and acute kidney and myocardial injury after noncardiac surgery: a retrospective cohort analysis. Anesthesiology. 2017;126:47–65. https://doi.org/10.1097/ALN.0000000000001432.

    Article  PubMed  Google Scholar 

  18. Walsh M, Devereaux PJ, Garg AX, et al. Relationship between intraoperative mean arterial pressure and clinical outcomes after noncardiac surgery: toward an empirical definition of hypotension. Anesthesiology. 2013;119:507–15. https://doi.org/10.1097/ALN.0b013e3182a10e26.

    Article  PubMed  Google Scholar 

  19. Stapelfeldt WH, Yuan H, Dryden JK, et al. The SLUScore: a novel method for detecting hazardous hypotension in adult patients undergoing noncardiac surgical procedures. Anesth Analg. 2017;124:1135–52. https://doi.org/10.1213/ANE.0000000000001797.

    Article  PubMed  PubMed Central  Google Scholar 

  20. Kato R, Pinsky MR. Personalizing blood pressure management in septic shock. Ann Intensive Care. 2015;5:41. https://doi.org/10.1186/s13613-015-0085-5.

    Article  PubMed  PubMed Central  Google Scholar 

  21. Borgaonkar MR, Hookey L, Hollingworth R, et al. Indicators of safety compromise in gastrointestinal endoscopy. Can J Gastroenterol. 2012;26:71–8.

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Bernd Saugel.

Ethics declarations

Conflict of interest

JYN and BS received refunds of travel expenses from CNSystems Medizintechnik AG (Graz, Austria). BS received honoraria for giving lectures from CNSystems Medizintechnik AG (Graz, Austria). All other authors have no conflict of interest to disclose. CNSystems Medizintechnik AG (Graz, Austria) provided the technical equipment needed for this study. The company was not involved in the study design, in the collection, analysis, and interpretation of data, writing of the manuscript, and in the decision to submit the manuscript for publication.

Ethical approval

This method comparison study was reviewed and approved by the ethics committee (Ethikkomission der Ärztekammer Hamburg, Hamburg, Germany). All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Nicklas, J.Y., Beckmann, D., Killat, J. et al. Continuous noninvasive arterial blood pressure monitoring using the vascular unloading technology during complex gastrointestinal endoscopy: a prospective observational study. J Clin Monit Comput 33, 25–30 (2019). https://doi.org/10.1007/s10877-018-0131-6

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10877-018-0131-6

Keywords

Navigation