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The neuronal dynamics underlying cognitive flexibility in set shifting tasks

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Abstract

The ability to switch attention from one aspect of an object to another or in other words to switch the “attentional set” as investigated in tasks like the “Wisconsin Card Sorting Test” is commonly referred to as cognitive flexibility. In this work we present a biophysically detailed neurodynamical model which illustrates the neuronal base of the processes related to this cognitive flexibility. For this purpose we conducted behavioral experiments which allow the combined evaluation of different aspects of set shifting tasks: uninstructed set shifts as investigated in Wisconsin-like tasks, effects of stimulus congruency as investigated in Stroop-like tasks and the contribution of working memory as investigated in “Delayed-Match-to-Sample” tasks. The work describes how general experimental findings are usable to design the architecture of a biophysical detailed though minimalistic model with a high orientation on neurobiological findings and how, in turn, the simulations support experimental investigations. The resulting model is able to account for experimental and individual response times and error rates and enables the switch of attention as a system inherent model feature: The switching process suggested by the model is based on the memorization of the visual stimuli and does not require any synaptic learning. The operation of the model thus demonstrates with at least a high probability the neuronal dynamics underlying a key component of human behavior: the ability to adapt behavior according to context requirements—cognitive flexibility.

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Authors and Affiliations

  1. Department Psychologie, LMU Munich, Leopoldstr. 13, D-80802, Munich, Germany

    Anja Stemme & Astrid Busch

  2. ICREA Research Professor, Computational Neuroscience, Universitat Pompeu Fabra, Passeig de Circumvallació 8, 08003, Barcelona, Spain

    Gustavo Deco

Authors
  1. Anja Stemme
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  2. Gustavo Deco
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  3. Astrid Busch
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Correspondence to Anja Stemme.

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Action Editor: Peter Dayan

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Stemme, A., Deco, G. & Busch, A. The neuronal dynamics underlying cognitive flexibility in set shifting tasks. J Comput Neurosci 23, 313–331 (2007). https://doi.org/10.1007/s10827-007-0034-x

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  • DOI: https://doi.org/10.1007/s10827-007-0034-x

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