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Cardiovascular complications in patients with idiopathic inflammatory myopathies: does heart matter in idiopathic inflammatory myopathies?

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Abstract

This review presents a detailed study of original researches and previously published reviews concerning cardiovascular involvement in idiopathic inflammatory myopathies (IIM). We aimed to summarize the current knowledge on the cardiac involvement in IIM, evaluate its impact on mortality and indicate areas still awaiting to be investigated. We searched MEDLINE database (until January 2019) and the reference lists of articles. Selection criteria included only published data, available in English, both original researches and reviews. Articles related to cardiovascular involvement in IIM were selected and analysed. The references were also screened, and relevant articles were included. Cardiovascular involvement is frequent in IIM but typically remains subclinical. Among far less prevalent symptomatic forms, congestive heart failure is the most common. Myocardium and conduction system seems to be predominantly affected. High rate of left ventricular diastolic dysfunction was observed. Non-specific changes of ST-T segment were the most common abnormalities in electrocardiography. Patients with IIM were more frequently affected by atrial fibrillation as compared with other autoimmune diseases. Increased risk of myocardial infarction was observed; furthermore, patients often develop comorbidities that enhance cardiovascular risk. Since cardiovascular disorders remain one of the major causes of death and subclinical involvement is frequent, active screening is justified. Growing availability of the novel imaging techniques may facilitate diagnosis. Correlation between myocardial involvement and the type of autoantibodies and impact of different therapeutic options on the progression of cardiovascular lesions require further studies.

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References

  1. Mandel DE, Malemud CJ, Askari AD (2017) Idiopathic inflammatory myopathies: a review of the classification and impact of pathogenesis. Int J Mol Sci 18(5):1084. Published 2017 May 18. https://doi.org/10.3390/ijms18051084

    Article  CAS  PubMed Central  Google Scholar 

  2. Marvi U, Chung L, Fiorentino DF (2012) Clinical presentation and evaluation of dermatomyositis. Indian J Dermatol 57(5):375–381. https://doi.org/10.4103/0019-5154.100486

    Article  PubMed  PubMed Central  Google Scholar 

  3. Lundberg IE, de Visser M, Werth VP (2018) Classification of myositis. Nat Rev Rheumatol 14(5):269–278. https://doi.org/10.1038/nrrheum.2018.41

    Article  PubMed  Google Scholar 

  4. H.Chwalińska-Sadowska, P. Mielnik. Interna Szczeklika 2016. Medycyna Praktyczna. Kraków 2016, pages 1965–1970

  5. Kang EH, Lee EB, Shin KC, Im CH, Chung DH, Han SK, Song YW (2005) Interstitial lung disease in patients with polymyositis, dermatomyositis and amyopathic dermatomyositis. Rheumatology (Oxford) 44(10):1282–1286. https://doi.org/10.1093/rheumatology/keh723

    Article  CAS  Google Scholar 

  6. Cavazzana I, Fredi M, Selmi C, Tincani A, Franceschini F (2017) The clinical and histological spectrum of idiopathic inflammatory myopathies. Clin Rev Allergy Immunol 52(1):88–98. https://doi.org/10.1007/s12016-015-8517-4

    Article  CAS  PubMed  Google Scholar 

  7. Pipitone N (2016) Value of MRI in diagnostics and evaluation of myositis. Curr Opin Rheumatol 28:625–630. https://doi.org/10.1097/BOR.0000000000000326

    Article  PubMed  Google Scholar 

  8. Tasca G, Monforte M, De Fino C, Kley RA, Ricci E, Mirabella M (2015) Magnetic resonance imaging pattern recognition in sporadic inclusion-body myositis. Muscle Nerve 52(6):956–962. https://doi.org/10.1002/mus.24661

    Article  PubMed  Google Scholar 

  9. Barsotti S, Lundberg IE (2018) Current treatment for myositis. Curr Treatm Opt Rheumatol 4(4):299–315. Published online 2018 Sep 15. https://doi.org/10.1007/s40674-018-0106-2

    Article  PubMed  PubMed Central  Google Scholar 

  10. Mavrogeni SI, Kitas GD, Dimitroulas T (2016) Cardiovascular magnetic resonance in rheumatology: current status and recommendations for use. Int J Cardiol 217:135–148. https://doi.org/10.1016/j.ijcard.2016.04.158

    Article  PubMed  Google Scholar 

  11. Chwalińska-Sadowska H, Mielnik P Zapalenie skórno-mięśniowe i wielomięśniowe. Dermatomyositis and polymyositis, Postępy Nauk Medycznych s2/2011, pages 15–22

  12. Pluk H, van Hoeve BJ, van Dooren SH, Stammen-Vogelzangs J, van der Heijden A, Schelhaas HJ et al Autoantibodies to cytosolic 5′-nucleotidase 1A in inclusion body myositis. https://doi.org/10.1002/ana.23822

  13. Gupta R, Wayangankar SA, Targoff IN, Hennebry TA (2011) Clinical cardiac involvement in idiopathic inflammatory myopathies: a systematic review. Int J Cardiol 148(3):261–270. https://doi.org/10.1016/j.ijcard.2010.08.013

    Article  PubMed  Google Scholar 

  14. Zhang L, Wang GC, Ma L, Zu N (2012) Cardiac involvement in adult polymyositis or dermatomyositis: a systematic review. Clin Cardiol 35(11):686–691. https://doi.org/10.1002/clc.22026

    Article  CAS  PubMed  Google Scholar 

  15. Lilleker JB, Vencovsky J, Wang G, Wedderburn LR, Diederichsen LP, Schmidt J, Oakley P, Benveniste O, Danieli MG, Danko K, Thuy NTP, Vazquez-del Mercado M, Andersson H, de Paepe B, deBleecker J, Maurer B, McCann L, Pipitone N, McHugh N, Betteridge ZE, New P, Cooper RG, Ollier WE, Lamb JA, Krogh NS, Lundberg IE, Chinoy H, all EuroMyositis contributors et al (2018) The EuroMyositis registry: an international collaborative tool to facilitate myositis research. Ann Rheum Dis 77(1):30–39. https://doi.org/10.1136/annrheumdis-2017-211868

    Article  PubMed  Google Scholar 

  16. Bienias P, Ciurzyński M, Korczak D, Pruszczyk P (2008) Zaburzenia rytmu i przewodzenia u osób z chorobami układowymi tkanki łącznej - Arrhythmias and conduction disturbances in patients with connective tissue diseases. Kardiol Pol 66:194–199

    PubMed  Google Scholar 

  17. Lundberg IE (2005) Cardiac involvement in autoimmune myositis and mixed connective tissue disease. Lupus. https://doi.org/10.1191/0961203305lu2205oa

  18. Taylor AJ, Wortham DC, Burge JR, Rogan KM (1993) The heart in opolymyositis: a prospective evaluation of 26 patients. Clin Cardiol 16(11):802–808. https://doi.org/10.1002/clc.4960161110

    Article  CAS  PubMed  Google Scholar 

  19. Cardiac involvement in polymyositis and dermatomyositis. Autoimmun Rev 2016;15(5):462–5. https://doi.org/10.1016/j.autrev.2016.01.015

  20. Allanore Y, Vignaux O, Arnaud L, Puéchal X, Pavy S, Duboc D, Legmann P, Kahan A (2006) Effects of corticosteroids and immunosuppressors on idiopathic inflammatory myopathy related myocarditis evaluated by magnetic resonance imaging. Ann Rheum Dis 65(2):249–252. https://doi.org/10.1136/ard.2005.038679

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  21. Haupt HM, Hutchins GM (1982) The heart and cardiac conduction system in polymyositis-dermatomyositis: a clinicopathologic study of 16 autopsied patients. Am J Cardiol 50(5):998–1006. https://doi.org/10.1016/0002-9149(82)90408-8

    Article  CAS  PubMed  Google Scholar 

  22. Denbow CE, Lie JT, Tancredi RG, Bunch TW (1979) Cardiac involvement in polymyositis: a clinicopathologic study of 20 autopsied patients. Arthritis Rheum 22(10):1088–1089. https://doi.org/10.1002/art.1780221007

    Article  CAS  PubMed  Google Scholar 

  23. Rosenbohm A, Buckert D, Gerischer N, Walcher T, Kassubek J, Rottbauer W, Ludolph AC, Bernhardt P (2015) Early diagnosis of cardiac involvement in idiopathic inflammatory myopathy by cardiac magnetic resonance tomography. J Neurol 262(4):949–956. https://doi.org/10.1007/s00415-014-7623-1

    Article  PubMed  Google Scholar 

  24. Diederichsen LP, Simonsen JA, Diederichsen AC, Hvidsten S, Hougaard M, Junker P, Søndergaard K, Lundberg IE, Tvede N, Sandgaard NC, Christensen AF, Dreyer L, Kay S, Eskerud KS, Petersen H, Ejstrup L, Jacobsen S et al (2016) Cardiac abnormalities in adult patients with polymyositis or dermatomyositis as assessed by noninvasive modalities. Arthritis Care Res (Hoboken) 68(7):1012–1020. https://doi.org/10.1002/acr.22772

    Article  CAS  Google Scholar 

  25. Wang H, Liu HX, Wang YL, Yu XQ, Chen XX, Cai L (2014) Left ventricular diastolic dysfunction in patients with dermatomyositis without clinically evident cardiovascular disease. J Rheumatol 41(3):495–500. https://doi.org/10.3899/jrheum.130346

    Article  PubMed  Google Scholar 

  26. Afzal A, Higgins RSD, Philbin EF (1999) Heart transplant for dilated cardiomyopathy associated with polymyositis. Heart. 82(4):e4. https://doi.org/10.1136/hrt.82.4.e4

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  27. Stern R, Godbold JH, Chess Q, Kagen LJ (1984) ECG abnormalities in polymyositis. Arch Intern Med 144(11):2185–2189

    Article  CAS  PubMed  Google Scholar 

  28. Deveza LM, Miossi R, de Souza FH, Shimabuco AY, Favarato MH, Grindler J, Shinjo SK (2016) Electrocardiographic changes in dermatomyositis and polymyositis. Rev Bras Reumatol Engl Ed 56(2):95–100. https://doi.org/10.1016/j.rbre.2014.08.012

    Article  PubMed  Google Scholar 

  29. Hebert CA, Byrnes TJ, Baethge BA, Wolf RE, Kinasewitz GT (1990) Exercise limitation in patients with polymyositis. Chest. 98(2):352–357. https://doi.org/10.1378/chest.98.2.352

    Article  CAS  PubMed  Google Scholar 

  30. Byrnes TJ, Baethge BA, Wolf RE (1991) Noninvasive cardiovascular studies in patients with inflammatory myopathy. Angiology. 42(10):843–848. https://doi.org/10.1177/000331979104201010

    Article  CAS  PubMed  Google Scholar 

  31. Bohan A, Peter JB, Bowman RL, Pearson CM (1977) Computer-assisted analysis of 153 patients with polymyositis and dermatomyositis. Medicine (Baltimore) 56(4):255–286. https://doi.org/10.1097/00005792-197707000-00001

    Article  CAS  Google Scholar 

  32. Hochberg MC, Feldman D, Stevens MB (1986) Adult onset polymyositis/dermatomyositis: an analysis of clinical and laboratory features and survival in 76 patients with a review of the literature. Semin Arthritis Rheum 15(3):168–178

    Article  CAS  PubMed  Google Scholar 

  33. Na SJ, Kim SM, Sunwoo IN, Choi YC (2009) Clinical characteristics and outcomes of juvenile and adult dermatomyositis. J Korean Med Sci 24(4):715–721. https://doi.org/10.3346/jkms.2009.24.4.715

    Article  PubMed  PubMed Central  Google Scholar 

  34. Gottdiener JS, Sherber HS, Hawley RJ, Engel WK (1978) Cardiac manifestations in polymyositis. Am J Cardiol 41(7):1141–1149. https://doi.org/10.1016/0002-9149(78)90871-8

    Article  CAS  PubMed  Google Scholar 

  35. Zhong Y, Bai W, Xie Q, Sun J, Tang H, Rao L (2018) Cardiac function in patients with polymyositis or dermatomyositis: a three-dimensional speckle-tracking echocardiography study. Int J Cardiovasc Imaging 34(5):683–693. https://doi.org/10.1007/s10554-017-1278-9

    Article  PubMed  Google Scholar 

  36. Oka M, Raasakka T.et al., Cardiac involvement in polymyositis, Scand J Rheumatol 1978;7(4):203–208.

  37. Lightfoot PR, Bharati S, Lev M (1977) Chronic dermatomyositis with intermittent trifascicular block. An electrophysiologic-conduction system correlation. Chest. 71(3):413–416. https://doi.org/10.1378/chest.71.3.413

    Article  CAS  PubMed  Google Scholar 

  38. Baek YS, Kim TH, Uhm JS, Kim JY, Pak HN, Lee MH, Joung B (2016) Prevalence and the clinical outcome of atrial fibrillation in patients with autoimmune rheumatic disease. Int J Cardiol 214:4–9. https://doi.org/10.1016/j.ijcard.2016.03.083

    Article  PubMed  Google Scholar 

  39. Barth Z, Nomeland Witczak B, Schwartz T, Gjesdal K, Flatø B, Koller A, Sanner H, Sjaastad I (2016) In juvenile dermatomyositis, heart rate variability is reduced, and associated with both cardiac dysfunction and markers of inflammation: a cross-sectional study median 13.5 years after symptom onset. Rheumatology (Oxford) 55(3):535–543. https://doi.org/10.1093/rheumatology/kev376

    Article  Google Scholar 

  40. Lundberg IE (2006) The heart in dermatomyositis and polymyositis. Rheumatology (Oxford) 45(Suppl 4):iv18–iv21. https://doi.org/10.1093/rheumatology/kel311

    Article  Google Scholar 

  41. Plazak W, Kopec G, Tomkiewicz-Pajak L, Rubis P, Dziedzic H, Suchon E, Kostkiewicz M, Olszowska M, Musial J, Podolec P (2011) Heart structure and function in patients with generalized autoimmune diseases: echocardiography with tissue Doppler study. Abstract Acta Cardiol 66(2):159–165. https://doi.org/10.2143/AC.66.2.2071246

    Article  Google Scholar 

  42. Lee KS, Kronbichler A, Eisenhut M, Lee KH, Shin JI (2018) Cardiovascular involvement in systemic rheumatic diseases: an integrated view for the treating physicians. Autoimmun Rev 17(3):201–214. https://doi.org/10.1016/j.autrev.2017.12.001

    Article  PubMed  Google Scholar 

  43. Chraibi S, Ibnabdeljalil H, Habbal R, Bennis A, Tahiri A, Chraibi N (1998) Pericardial tamponade as the first manifestation of dermatopolymyositis. Ann Med Interne (Paris) 149(7):464–466

    CAS  Google Scholar 

  44. Bhatia P, Constantinescu F, Walitt B (2010) Pericardial tamponade as the initial presentation in a patient with polymyositis. J Clin Rheumatol 16(6):298–299. https://doi.org/10.1097/RHU.0b013e3181ef6ef8

    Article  PubMed  Google Scholar 

  45. Zöller B, Li X, Sundquist J, Sundquist K (2012) Risk of subsequent coronary heart disease in patients hospitalized for immune-mediated diseases: a nationwide follow-up study from Sweden. PLoS One 7(3):e33442. https://doi.org/10.1371/journal.pone.0033442

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  46. Linos E, Fiorentino D, Lingala B, Krishnan E, Chung L (2013) Atherosclerotic cardiovascular disease and dermatomyositis: an analysis of the Nationwide Inpatient Sample survey. Arthritis Res Ther 15(1):R7. Published 2013 Jan 8. https://doi.org/10.1186/ar4135

    Article  PubMed  PubMed Central  Google Scholar 

  47. Tisseverasinghe A, Bernatsky S, Pineau CA (2009) Arterial events in persons with dermatomyositis and polymyositis. J Rheumatol 36(9):1943–1946. https://doi.org/10.3899/jrheum.090061

    Article  PubMed  Google Scholar 

  48. Rai SK, Choi HK, Sayre EC, Aviña-Zubieta JA (2016) Risk of myocardial infarction and ischaemic stroke in adults with polymyositis and dermatomyositis: a general population-based study. Rheumatology (Oxford) 55(3):461–469. https://doi.org/10.1093/rheumatology/kev336

    Article  Google Scholar 

  49. Lai YT, Dai YS, Yen MF, Chen LS, Chen HH, Cooper RG, Pan SL (2013) Dermatomyositis is associated with an increased risk of cardiovascular and cerebrovascular events: a Taiwanese population-based longitudinal follow-up study. Br J Dermatol 168(5):1054–1059. https://doi.org/10.1111/bjd.12245

    Article  PubMed  Google Scholar 

  50. DeVere R, Bradley WG (1975) Polymyositis: its presentation, morbidity and mortality. Brain. 98(4):637–666. https://doi.org/10.1093/brain/98.4.637

    Article  CAS  PubMed  Google Scholar 

  51. Riemekasten G, Opitz C, Audring H, Barthelmes H, Meyer R, Hiepe F, Burmester GR (1999) Beware of the heart: the multiple picture of cardiac involvement in myositis. Rheumatology (Oxford) 38(11):1153–1157. https://doi.org/10.1093/rheumatology/38.11.1153

    Article  CAS  Google Scholar 

  52. Diederichsen LP (2017) Cardiovascular involvement in myositis. Curr Opin Rheumatol 29(6):598–603. https://doi.org/10.1097/BOR.0000000000000442

    Article  PubMed  Google Scholar 

  53. Carruthers EC, Choi HK, Sayre EC, Aviña-Zubieta JA (2016) Risk of deep venous thrombosis and pulmonary embolism in individuals with polymyositis and dermatomyositis: a general population-based study. Ann Rheum Dis 75(1):110–116. https://doi.org/10.1136/annrheumdis-2014-205800

    Article  PubMed  Google Scholar 

  54. Ungprasert P, Cheungpasitporn W, Wijarnpreecha K, Ahuja W, Ratanasrimetha P, Thongprayoon C (2015) Risk of ischemic stroke in patients with polymyositis and dermatomyositis: a systematic review and meta-analysis. Rheumatol Int 35(5):905–909. https://doi.org/10.1007/s00296-014-3166-0

    Article  CAS  PubMed  Google Scholar 

  55. Zöller B, Li X, Sundquist J, Sundquist K (2012) Risk of subsequent ischemic and hemorrhagic stroke in patients hospitalized for immune-mediated diseases: a nationwide follow-up study from Sweden. BMC Neurol 12:41. https://doi.org/10.1186/1471-2377-12-41

    Article  PubMed  PubMed Central  Google Scholar 

  56. Limaye VS, Lester S, Blumbergs P, Roberts-Thomson PJ (2010) Idiopathic inflammatory myositis is associated with a high incidence of hypertension and diabetes mellitus. Int J Rheum Dis 13(2):132–137. https://doi.org/10.1111/j.1756-185X.2010.01470.x

    Article  PubMed  Google Scholar 

  57. Lega JC, Reynaud Q, Belot A, Fabien N, Durieu I, Cottin V (2015) Idiopathic inflammatory myopathies and the lung. Eur Respir Rev 24(136):216–238. https://doi.org/10.1183/16000617.00002015

    Article  PubMed  Google Scholar 

  58. Minai OA (2009) Pulmonary hypertension in polymyositis-dermatomyositis: clinical and hemodynamic characteristics and response to vasoactive therapy. Lupus. 18(11):1006–1010. https://doi.org/10.1177/0961203309102822

    Article  CAS  PubMed  Google Scholar 

  59. Thakkar V, Lau EM (2016) Connective tissue disease related pulmonary arterial hypertension. Best Pract Res Clin Rheumatol 30(1):22–38. https://doi.org/10.1016/j.berh.2016.03.004

    Article  PubMed  Google Scholar 

  60. Wang H, Liu T, Cai YY, Luo L, Wang M, Yang M, Cai L (2015) Pulmonary hypertension in polymyositis. Clin Rheumatol 34(12):2105–2112. https://doi.org/10.1007/s10067-015-3095-7

    Article  PubMed  Google Scholar 

  61. Bunch TW, Tancredi RG, Lie JT (1981) Pulmonary hypertension in polymyositis. Chest. 79(1):105–107. https://doi.org/10.1378/chest.79.1.105

    Article  CAS  PubMed  Google Scholar 

  62. Sanges S, Yelnik CM, Sitbon O, Benveniste O, Mariampillai K, Phillips-Houlbracq M et al (2016) Pulmonary arterial hypertension in idiopathic inflammatory myopathies, data from the French pulmonary hypertension registry and review of the literature. Medicine (Baltimore) 95(39):e4911. Published online 2016 Sep 30. https://doi.org/10.1097/MD.0000000000004911

    Article  Google Scholar 

  63. Guerra F, Gelardi C, Capucci A, Gabrielli A, Danieli MG (2017) Subclinical cardiac dysfunction in polymyositis and dermatomyositis: a speckle-tracking case-control study. J Rheumatol 44(6):815–821. https://doi.org/10.3899/jrheum.161311

    Article  CAS  PubMed  Google Scholar 

  64. Lundberg IE, Tjärnlund A, Bottai M, Werth VP, Pilkington C, Visser M, Alfredsson L, Amato AA, Barohn RJ, Liang MH, Singh JA, Aggarwal R, Arnardottir S, Chinoy H, Cooper RG, Dankó K, Dimachkie MM, Feldman BM, Torre IG, Gordon P, Hayashi T, Katz JD, Kohsaka H, Lachenbruch PA, Lang BA, Li Y, Oddis CV, Olesinska M, Reed AM, Rutkowska-Sak L, Sanner H, Selva-O'Callaghan A, Song YW, Vencovsky J, Ytterberg SR, Miller FW, Rider LG, International Myositis Classification Criteria Project consortium, The Euromyositis register and The Juvenile Dermatomyositis Cohort Biomarker Study and Repository (JDRG) (UK and Ireland) et al (2017) 2017 European League Against Rheumatism/American College of Rheumatology classification criteria for adult and juvenile idiopathic inflammatory myopathies and their major subgroups. Ann Rheum Dis 76(12):1955–1964. https://doi.org/10.1136/annrheumdis-2017-211468

    Article  PubMed  Google Scholar 

  65. Chen F, Peng Y, Chen M (2018) Diagnostic approach to cardiac involvement in idiopathic inflammatory myopathies. Int Heart J 59(2):256–262. https://doi.org/10.1536/ihj.17-204

    Article  CAS  PubMed  Google Scholar 

  66. Hughes M, Lilleker JB, Herrick AL, Chinoy H (2015) Cardiac troponin testing in idiopathic inflammatory myopathies and systemic sclerosis-spectrum disorders: biomarkers to distinguish between primary cardiac involvement and low grade skeletal muscle disease activity. Ann Rheum Dis 74(5):795–798. https://doi.org/10.1136/annrheumdis-2014-206812

    Article  CAS  PubMed  Google Scholar 

  67. Aggarwal R, Lebiedz-Odrobina D, Sinha A, Manadan A, Case JP (2009) Serum cardiac troponin T, but not troponin I, is elevated in idiopathic inflammatory myopathies. J Rheumatol 36(12):2711–2714. https://doi.org/10.3899/jrheum.090562

    Article  CAS  PubMed  Google Scholar 

  68. Lilleker JB, Diederichsen ACP, Jacobsen S, Guy M, Roberts ME, Sergeant JC, Cooper RG, Diederichsen LP, Chinoy H (2018) Using serum troponins to screen for cardiac involvement and assess disease activity in the idiopathic inflammatory myopathies. Rheumatology (Oxford) 57(6):1041–1046. https://doi.org/10.1093/rheumatology/key031

    Article  CAS  Google Scholar 

  69. Fisher C, Agrawal S, Wong WM, Fahie-Wilson M, Dasgupta B (2010) Clinical observations on the significance of raised cardiac troponin-T in patients with myositis of varying etiologies seen in rheumatology practice. Clin Rheumatol 29(10):1107–1111. https://doi.org/10.1007/s10067-010-1511-6

    Article  PubMed  Google Scholar 

  70. Yin G, Mao L, Cen XM, Yang M, Xie QB (2011) Application value of combining brain natriuretic peptide, creatine phosphokinase and echocardiogram in the evaluation of polymyositis-related chronic heart failure. Sichuan Da Xue Xue Bao Yi Xue Ban 42(5):646–648 660

    CAS  PubMed  Google Scholar 

  71. Behan WM, Behan PO, Gairns J (1987) Cardiac damage in polymyositis associated with antibodies to tissue ribonucleoproteins. Br Heart J 57(2):176–180. https://doi.org/10.1136/hrt.57.2.176

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  72. Hengstman GJ, ter Laak HJ, Vree Egberts WT, Lundberg IE, Moutsopoulos HM, Vencovsky J, Doria A, Mosca M, van Venrooij W, van Engelen B et al (2006) Anti-signal recognition particle autoantibodies: marker of a necrotising myopathy. Ann Rheum Dis 65(12):1635–1163. https://doi.org/10.1136/ard.2006.052191

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  73. Maeda MH, Tsuji S, Shimizu J (2012) Inflammatory myopathies associated with anti-mitochondrial antibodies. Brain. 135(Pt 6):1767–1777. https://doi.org/10.1093/brain/aws106

    Article  PubMed  Google Scholar 

  74. Albayda J, Khan A, Casciola-Rosen L, Corse AM, Paik JJ, Christopher-Stine L (2018) Inflammatory myopathy associated with anti-mitochondrial antibodies: a distinct phenotype with cardiac involvement. Semin Arthritis Rheum 47(4):552–556. https://doi.org/10.1016/j.semarthrit.2017.06.004

    Article  CAS  PubMed  Google Scholar 

  75. Yamanaka T, Fukatsu T, Ichinohe Y, Hirata Y (2017) Antimitochondrial antibodies-positive myositis accompanied by cardiac involvement. BMJ Case Rep 2017:bcr2016218469. https://doi.org/10.1136/bcr-2016-218469

    Article  PubMed  PubMed Central  Google Scholar 

  76. Touma Z, Arayssi T, Kibbi L, Masri AF (2008) Successful treatment of cardiac involvement in dermatomyositis with rituximab. Joint Bone Spine 75(3):334–337. https://doi.org/10.1016/j.jbspin.2007.05.011

    Article  CAS  PubMed  Google Scholar 

  77. Marie I (2012) Morbidity and mortality in adult polymyositis and dermatomyositis. Curr Rheumatol Rep 14(3):275–285. https://doi.org/10.1007/s11926-012-0249-3

    Article  CAS  PubMed  Google Scholar 

  78. Dankó K, Ponyi A, Constantin T, Borgulya G, Szegedi G (2004) Long-term survival of patients with idiopathic inflammatory myopathies according to clinical features: a longitudinal study of 162 cases. Medicine (Baltimore) 83(1):35–42. https://doi.org/10.1097/01.md.0000109755.65914.5e

    Article  Google Scholar 

  79. Danieli MG, Gambini S, Pettinari L, Logullo F, Veronesi G, Gabrielli A (2014) Impact of treatment on survival in polymyositis and dermatomyositis. A single-centre long-term follow-up study. Autoimmun Rev 13(10):1048–1054. https://doi.org/10.1016/j.autrev.2014.08.023

    Article  PubMed  Google Scholar 

  80. Kuo CF, See LC, Yu KH, Chou IJ, Chang HC, Chiou MJ, Luo SF (2011) Incidence, cancer risk and mortality of dermatomyositis and polymyositis in Taiwan: a nationwide population study. Br J Dermatol 165(6):1273–1279. https://doi.org/10.1111/j.1365-2133.2011.10595.x

    Article  PubMed  Google Scholar 

  81. Maugars YM, Berthelot JM, Abbas AA, Mussini JM, Nguyen JM, Prost AM (1996) Long-term prognosis of 69 patients with dermatomyositis or polymyositis. Clin Exp Rheumatol 14(3):263–274

    CAS  PubMed  Google Scholar 

  82. Xiao Y, Zuo X, You Y, Luo H, Duan L, Zhang W, Li Y, Xie Y, Zhou Y, Ning W, Li T, Liu S, Zhu H, Jiang Y, Wu S, Zhao H et al (2016) Investigation into the cause of mortality in 49 cases of idiopathic inflammatory myopathy: a single center study. Exp Ther Med 11(3):885–889. https://doi.org/10.3892/etm.2016.3006

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  83. Sultan SM, Ioannou Y, Moss K, Isenberg DA (2002) Outcome in patients with idiopathic inflammatory myositis: morbidity and mortality. Rheumatology (Oxford) 41(1):22–26. https://doi.org/10.1093/rheumatology/41.1.22

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Rheumatology, Medical University of Lodz, ul. Pieniny 30, 92-115, Łódź, Poland

    Aleksandra Halina Opinc, Zuzanna Małgorzata Łukasik & Joanna Samanta Makowska

  2. Department of Intensive Care, Cardiology, Medical University of Lodz, ul. Pomorska 251, 92-213, Łódź, Poland

    Marcin Adam Makowski

Authors
  1. Aleksandra Halina Opinc
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  2. Marcin Adam Makowski
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  3. Zuzanna Małgorzata Łukasik
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  4. Joanna Samanta Makowska
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Correspondence to Joanna Samanta Makowska.

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Opinc, A.H., Makowski, M.A., Łukasik, Z.M. et al. Cardiovascular complications in patients with idiopathic inflammatory myopathies: does heart matter in idiopathic inflammatory myopathies?. Heart Fail Rev 26, 111–125 (2021). https://doi.org/10.1007/s10741-019-09909-8

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