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Associations of tea and coffee consumption with prostate cancer risk

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Abstract

Purpose

Tea and coffee contain bioactive compounds and both beverages have recently been associated with a reduced risk of prostate cancer (PCa).

Methods

We studied associations of tea and coffee consumption with PCa risk in a population-based case–control study from King County, Washington, USA. Prostate cancer cases were diagnosed in 2002–2005 and matched to controls by 5-year age groups. Logistic regression was used to generate odds ratios (ORs) and 95 % confidence intervals (CIs).

Results

Among controls, 19 and 58 % consumed at least one cup per day of tea and coffee, respectively. The analysis of tea included 892 cases and 863 controls, and tea consumption was associated with a reduced overall PCa risk with an adjusted OR of 0.63 (95 % CI: 0.45, 0.90; P for trend = 0.02) for men in the highest compared to lowest category of tea intake (≥2 cups/day vs. ≤1 cup/week). Risk estimates did not vary substantially by Gleason grade or disease stage. Coffee consumption was not associated with risk of overall PCa or PCa in subgroups defined by tumor grade or stage.

Conclusions

Our results contribute further evidence that tea consumption may be a modifiable exposure that reduces PCa risk.

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Acknowledgments

This work was supported by grants from the National Cancer Institute (R01-CA092579) and the Dutch Cancer Society (UM 2009-4556). Additional support was provided by the Fred Hutchinson Cancer Research Center and the Prostate Cancer Foundation. The sponsors of the study had no role in the data analysis, data interpretation, and writing of the report.

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Authors and Affiliations

  1. Department of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands

    Milan S. Geybels

  2. Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, 1100 Fairview Avenue N, M4‐B874, Seattle, WA, 98109‐1024, USA

    Marian L. Neuhouser & Janet L. Stanford

  3. Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA, USA

    Marian L. Neuhouser & Janet L. Stanford

Authors
  1. Milan S. Geybels
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  2. Marian L. Neuhouser
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  3. Janet L. Stanford
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Corresponding author

Correspondence to Janet L. Stanford.

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Geybels, M.S., Neuhouser, M.L. & Stanford, J.L. Associations of tea and coffee consumption with prostate cancer risk. Cancer Causes Control 24, 941–948 (2013). https://doi.org/10.1007/s10552-013-0170-8

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  • DOI: https://doi.org/10.1007/s10552-013-0170-8

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