A mock circulatory system for simulating physiological characteristics of the cardiovascular system of pediatric heart failure patients is described. The system can also be used for preclinical testing of pediatric ventricular assist devices based on implantable rotary blood pumps.
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Lorts, A., Zafar, F., Adachi, I., and Morales, D. L. S., “Mechanical assist devices in neonates and infants,” Seminars in Thoracic and Cardiovascular Surgery, Pediatric Cardiac Surgery Annual, 17, No. 1, 91-95 (2014).
Jhun, C. S., Reibson, J. D., and Cysyk, J. P., “Effective ventricular unloading by left ventricular assist device varies with stage of heart failure. Cardiac simulator study,” ASAIO Journal, 57, No. 5, 407-413 (2011).
Vandenberghe, S., Shu, F., Arnold, D. K., and Antaki, J. F., “A simple, economical, and effective portable paediatric mock circulatory system,” Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, 225, 648-656 (2011).
Rossano, J. W., Dipchand, A. I., Edwards, L. B., Goldfarb, S., Kucheryavaya, A. Y., Levvey, B. J., Lund, L. H., Meiser, B., Yusen, R. D., and Stehlik, J., “Registry of the International Society for Heart and Lung Transplantation: Nineteenth pediatric heart transplantation report – 2016; Focus theme: Primary diagnostic indications for transplant,” J. Heart Lung Transplant., 35, No. 10, 1185-1195 (2016).
Rossano, J. W., Lorts, A., VanderPluym, C. J., Jeema, A., Guleserian, K. J., Bleiweis, M. S., Reinhartz, O., Blume, E. D., Rosenthal, D. N., Naftel, D. C., Cantor, R. S., and Kirklin, J. K., “Outcomes of pediatric patients supported with continuous-flow ventricular assist devices: A report from the Pediatric Interagency Registry for Mechanical Circulatory Support (PediMACS),” J. Heart Lung Transplant., 35, No. 5, 585-590 (2016).
Timms, D. L., Gregory, S. D., Greatrex, N. A., Pearcy, M. J., Fraser, J. F., and Steinseifer, U., “A compact mock circulation loop for the in vitro testing of cardiovascular devices,” Artif. Organs, 35, No. 4, 384-391 (2010).
Huang, F., Ruan, X., Zou, J., Qian, W., and Fu, X., “A fast building and effective hydraulic pediatric mock circulatory system for the evaluation of a left ventricular assist device,” ASAIO Journal, 59, 575-585 (2013).
Pantalos, G. M., Ionan, C., Koenig, S. C., Gillars, K. J., Horrell, T., Sahetya, S., Colyer, J., and Gray, L. A. J., “Expanded pediatric cardiovascular simulator for research and training,” ASAIO Journal, 56, 67-72 (2010).
Sapin, M. R. and Sivoglazov, V. I., Human Anatomy and Physiology (with regard for age peculiarities of child’s body) [in Russian], Akademiya, Moscow (2002).
Munoz, R., Schmitt, C. G., Roth, S. J., and Cruz E. (eds.) Handbook of Pediatric Cardiovascular Drugs, Springer, London (2008).
Vetter, V. L. and Bell, L. M. (ed.) Pediatric Cardiology: The Requisites in Pediatrics, Elsevier, Philadelphia (2006).
Denisov, M. V., Selishchev, S. V., Telyshev, D. V., and Frolova, E. A., “Development of medical and technical requirements and simulation of the flow−pressure characteristics of the Sputnik pediatric rotary blood pump,” Biomed. Eng., 50, No. 5, 296-299 (2017).
Bockeria, L. A., Bockeria, O. L., Selishchev, S. V., Telyshev, D. V., Le, T. G., Satyukova, A. S., Shvartz, V. A., and Glushko, L. A., “Experimental determination of the normalized index of hemolysis for the Sputnik implantable pediatric rotary blood pump,” Biomed. Eng., 50, No. 6, 416-419 (2017).
Telyshev, D. V., Denisov, M. V., and Selishchev, S. V., “The effect of rotor geometry on the H−Q curves of the Sputnik implantable pediatric rotary blood pump,” Biomed. Eng., 50, No. 6, 420-424 (2017).
Porphiriev, A. O., Pugovkin, A. A., Selishchev, S. V., and Telyshev D. V., “Development of artificial ventricles for modeling the cardiovascular system,” Biomed. Eng., 49, No. 6, 331-334 (2016).
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Translated from Meditsinskaya Tekhnika, Vol. 51, No. 2, Mar.-Apr., 2017, pp. 5-9.
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Telyshev, D.V., Pugovkin, A.A. & Selishchev, S.V. A Mock Circulatory System for Testing Pediatric Rotary Blood Pumps. Biomed Eng 51, 83–87 (2017). https://doi.org/10.1007/s10527-017-9689-4
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DOI: https://doi.org/10.1007/s10527-017-9689-4