Intrasplenic allogeneic transplantation of multipotent stromal cells from the umbilical cord stimulates hepatocyte proliferation and promotes recovery of liver weight in rats after subtotal resection (80% organ weight). It can be hypothesized that this effect of multipotent stromal cells is due to more rapid recovery of the number of mitochondria and normalization of mitochondrial function of liver hepatocytes.
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Translated from Kletochnye Tekhnologii v Biologii i Meditsine, No. 4, pp. 253–259, October, 2014
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El’chaninov, A.V., Volodina, M.A., Arutyunyan, I.V. et al. Effect of Multipotent Stromal Cells on the Function of Cell Mitochondria in Regenerating Liver. Bull Exp Biol Med 158, 566–572 (2015). https://doi.org/10.1007/s10517-015-2808-x
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DOI: https://doi.org/10.1007/s10517-015-2808-x