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The epidemiology of Parkinson’s disease in the Italian region Friuli Venezia Giulia: a population-based study with administrative data

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Abstract

Parkinson’s disease is known to pose a relevant burden to society in industrialized countries. However, not much research has been conducted on the epidemiology of this disease in Italy. Our aim was to estimate the incidence rate and prevalence of Parkinson’s disease in the Italian Friuli Venezia Giulia region using administrative health-related databases. Five regional administrative databases (hospitalizations, exemptions from medical charges, drug prescriptions, nursing homes, and home visits) were individually linked with one another through an anonymous stochastic univocal key. Using a pre-defined algorithm, incident and prevalent cases of Parkinson’s disease were identified for the year 2016. The estimated regional incidence rate was 0.28 new cases/1000 person-years; prevalence was 3.89/1000 inhabitants. Both increased with increasing age and were higher among males than among females. A considerable proportion of prevalent cases was admitted to the hospital or nursing home in 2016, whereas only a few received home visits by health professionals. The incidence and prevalence of the disease were considerable, especially in the older population, indicating the need to develop multidisciplinary models to care for patients living in the region.

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References

  1. Lee A, Gilbert RM (2016) Epidemiology of Parkinson disease. Neurol Clin 34(4):955–965. https://doi.org/10.1016/j.ncl.2016.06.012

    Article  PubMed  Google Scholar 

  2. Baldereschi M, Di Carlo A, Rocca WA, Vanni P, Maggi S, Perissinotto E, Grigoletto F, Amaducci L, Inzitari D (2000) Parkinson’s disease and parkinsonism in a longitudinal study: two-fold higher incidence in men. ILSA Working Group. Italian longitudinal study on aging. Neurology 55(9):1358–1363. https://doi.org/10.1212/WNL.55.9.1358

    Article  CAS  PubMed  Google Scholar 

  3. Chillag-Talmor O, Giladi N, Linn S, Gurevich T, El-Ad B, Silverman B, Friedman N, Peretz C (2011) Use of a refined drug tracer algorithm to estimate prevalence and incidence of Parkinson’s disease in a large Israeli population. J Parkinsons Dis 1(1):35–47. https://doi.org/10.3233/JPD-2011-11024

    PubMed  Google Scholar 

  4. Huber CA, Szucs TD, Rapold R, Reich O (2013) Identifying patients with chronic conditions using pharmacy data in Switzerland: an updated mapping approach to the classification of medications. BMC Public Health 13(1):1030. https://doi.org/10.1186/1471-2458-13-1030

    Article  PubMed  PubMed Central  Google Scholar 

  5. Chini F, Pezzotti P, Orzella L, Borgia P, Guasticchi G (2011) Can we use the pharmacy data to estimate the prevalence of chronic conditions? A comparison of multiple data sources. BMC Public Health 11(1):688. https://doi.org/10.1186/1471-2458-11-688

    Article  PubMed  PubMed Central  Google Scholar 

  6. Moisan F, Kab S, Mohamed F, Canonico M, Le Guern M, Quintin C, Carcaillon L, Nicolau J, Duport N, Singh-Manoux A, Boussac-Zarebska M, Elbaz A (2016) Parkinson disease male-to-female ratios increase with age: French nationwide study and meta-analysis. J Neurol Neurosurg Psychiatry 87(9):952–957. https://doi.org/10.1136/jnnp-2015-312283

    Article  PubMed  Google Scholar 

  7. Baldacci F, Policardo L, Rossi S, Ulivelli M, Ramat S, Grassi E, Palumbo P, Giovannelli F, Cincotta M, Ceravolo R, Sorbi S, Francesconi P, Bonuccelli U (2015) Reliability of administrative data for the identification of Parkinson’s disease cohorts. Neurol Sci 36(5):783–786. https://doi.org/10.1007/s10072-015-2062-z

    Article  PubMed  Google Scholar 

  8. Tominz R, Marin L, Mezzarobba S (2015) Estimate of the prevalence of Parkinson’s disease by using electronic health archives. Recenti Prog Med 106(2):97–102. https://doi.org/10.1701/1790.19496

    PubMed  Google Scholar 

  9. Ministero della Salute (2017) Elenco malattie e condizioni croniche e invalidanti, http://www.trovanorme.salute.gov.it/norme/renderPdfspring?seriegu=SGdatagu=18/03/2017redaz=17A02015artp=13art=1subart=1subart1=10vers=1prog=001 Accessed 21 Nov. 2017

  10. Ministero della Salute (2017) Elenco malattie rare esentate dalla partecipazione al costo, http://www.trovanorme.salute.gov.it/norme/renderPdfspring?seriegu=SGdatagu=18/03/2017redaz=17A02015artp=12art=1subart=1subart1=10vers=1prog=001 Accessed 21 Nov. 2017

  11. Guo S, Huang J, Jiang H, Han C, Li J, Xu X, Zhang G, Lin Z, Xiong N, Wang T (2017) Restless legs syndrome: from pathophysiology to clinical diagnosis and management. Front Aging Neurosci 9(171). https://doi.org/10.3389/fnagi.2017.00171

  12. Paviour DC, Surtees RA, Lees AJ (2004) Diagnostic considerations in juvenile parkinsonism. Mov Disord 19(2):123–135. https://doi.org/10.1002/mds.10644

    Article  PubMed  Google Scholar 

  13. Deloitte Access Economics (2015). Living with Parkinson’s disease. An updated economic analysis 2014. Parkinson’s Australia Inc.

  14. Boersma I, Jones J, Coughlan C, Carter J, Bekelman D, Miyasaki J, Kutner J, Kluger B (2017) Palliative care and Parkinson’s disease: caregiver perspectives. J Palliat Med 20(9):930–938. https://doi.org/10.1089/jpm.2016.0325

    Article  PubMed  Google Scholar 

  15. Kluger BM, Fox S, Timmons S, Katz M, Galifianakis NB, Subramanian I, Carter JH, Johnson MJ, Richfield EW, Bekelman D, Kutner JS, Miyasaki J (2017) Palliative care and Parkinson’s disease: meeting summary and recommendations for clinical research. Parkinsonism Relat Disord 37:19–26. https://doi.org/10.1016/j.parkreldis.2017.01.008

    Article  PubMed  Google Scholar 

  16. Fereshtehnejad SM (2016) Strategies to maintain quality of life among people with Parkinson’s disease: what works? Neurodegener Dis Manag 6(5):399–415. https://doi.org/10.2217/nmt-2016-0020

    Article  PubMed  Google Scholar 

  17. Qamar MA, Harington G, Trump S, Johnson J, Roberts F, Frost E (2017) Multidisciplinary Care in Parkinson’s disease. Int Rev Neurobiol 132:511–523. https://doi.org/10.1016/bs.irn.2017.02.001

    Article  PubMed  Google Scholar 

  18. Istat (2014) Annuario statistico italiano. Istat, Roma

    Google Scholar 

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Authors and Affiliations

  1. Hygiene and Clinical Epidemiology Unit, “S. Maria della Misericordia” University Hospital of Udine, Udine, Italy

    Francesca Valent & Annarita Tullio

  2. Epidemiological Service, Central Health Directorate, Udine, Friuli Venezia Giulia Region, Italy

    Francesca Valent & Stefania Del Zotto

  3. Neurology Unit, Neuroscience Department, “S. Maria della Misericordia” University Hospital of Udine, Udine, Italy

    Grazia Devigili, Sara Rinaldo & Roberto Eleopra

Authors
  1. Francesca Valent
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  2. Grazia Devigili
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  3. Sara Rinaldo
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  4. Stefania Del Zotto
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  5. Annarita Tullio
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  6. Roberto Eleopra
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Corresponding author

Correspondence to Francesca Valent.

Ethics declarations

This article does not contain any studies with human or animal subjects performed by any of the authors.

Since this analysis was based on anonymous administrative data, patients’ informed consent and Ethical Committee approval were not required in Italy.

Conflicts of interest

The authors declare that they have no conflict of interest.

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Valent, F., Devigili, G., Rinaldo, S. et al. The epidemiology of Parkinson’s disease in the Italian region Friuli Venezia Giulia: a population-based study with administrative data. Neurol Sci 39, 699–704 (2018). https://doi.org/10.1007/s10072-018-3273-x

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  • DOI: https://doi.org/10.1007/s10072-018-3273-x

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