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Healing of intrabony defects following treatment with an oily calcium hydroxide suspension (Osteoinductal). A controlled clinical study

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Abstract

The purpose of the present clinical study was to evaluate the healing of deep intrabony defects following the application of an oily calcium hydroxide suspension (OCHS). Thirty patients suffering from chronic periodontitis, each of whom displayed one intrabony defect, were randomly treated with access flap surgery (AFS) and the application of OCHS (test) or with AFS alone (control). The following clinical parameters were recorded at baseline and at 6 months after therapy: plaque index, gingival index, bleeding on probing, probing depth (PD), gingival recession, and clinical attachment level (CAL). No differences in any of the investigated parameters were observed at baseline between the two groups. At 6 months after therapy, the test group showed a reduction in mean PD from 7.7±1.5 to 2.9±0.9 mm (P<0.001) and a change in mean CAL from 9.6±2.1 to 5.5±2.5 mm (P<0.001). In the control group, the mean PD was reduced from 6.9±0.9 to 3.7±0.9 mm (P<0.001) and the mean CAL changed from 8.5±2.5 to 6.4±2.7 mm (P<0.001). OCHS resulted in statistically significant higher PD reductions (P<0.01) and CAL gains (P<0.05) than AFS alone. Within the limits of the present study, it can be concluded that: (1) at 6 months after surgery both therapies resulted in statistically significant PD reductions and CAL gains and (2) treatment with OCHS resulted in statistically significant higher CAL gains than treatment with AFS alone.

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Authors and Affiliations

  1. Department of Periodontology, Victor-Babes University of Medicine, Timisoara, Romania

    Stefan-Ioan Stratul

  2. Department of Oral Surgery, Heinrich Heine University, Düsseldorf, Germany

    Frank Schwarz & Jürgen Becker

  3. Department of Conservative Dentistry and Periodontology, Johannes-Gutenberg University, Mainz, Germany

    Britta Willershausen

  4. Department of Periodontology, Radboud University Medical Center, P.O. Box 9101, Internal Postal Code 117, 6500 Nijmegen, Philips van Leydenlaan 25, The Netherlands

    Anton Sculean

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  1. Stefan-Ioan Stratul
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  2. Frank Schwarz
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  4. Britta Willershausen
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Correspondence to Anton Sculean.

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Stratul, SI., Schwarz, F., Becker, J. et al. Healing of intrabony defects following treatment with an oily calcium hydroxide suspension (Osteoinductal). A controlled clinical study. Clin Oral Invest 10, 55–60 (2006). https://doi.org/10.1007/s00784-005-0024-1

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  • DOI: https://doi.org/10.1007/s00784-005-0024-1

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