Abstract
We report a case of Castleman’s disease which developed in the posterior mediastinum, with a review of the Japanese literature. A 19-year-old female patient with asthma was pointed out to have an abnormal shadow in the right posterior mediastinum on chest X-ray. We had tried to perform thoracoscopic surgery for this tumor, but we had to convert the surgical approach from thoracoscopy to a thoracotomy because of both tight adhesion of the tumor and muscle and profuse bleeding from the tumor. The tumor was diagnosed to be the hyaline vascular type of Castleman’s disease histopathologically. In the Japanese literature, Castleman’s disease, which develops in the posterior mediastinum, has been reported to often accompany tight adhesion between the tumor and surrounding tissue, and profuse bleeding thus cannot be avoided at surgery. The large amount of bleeding observed during the surgery of a patient with Castleman’s disease in the posterior mediastinum may be due to tight adhesion and hypervascularity of the tumor. Therefore, care should be exercised in choosing the surgical approach if Castleman’s disease is suspected in cases of posterior mediastinal tumor.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Castlemankw B, Iverson L, Menendez VP (1956) Localized mediastinal lymph-node hyperplasia resembling thymoma. Cancer 9: 822–830
Inada K, Hamazaki M (1958) Localized mediastinal lymph-node hyperplasia resembling thymoma. A case report. Ann Surg 147: 409–413
Lattes R, Pachter MR (1962) Benign lymphoid masses of probable hamartomatous nature. Analysis of 12 cases. Cancer 15:197–214
Abell MR (1957) Lymphnodal hamartoma versus thymic choristoma of pulmonary hilum. Arch Pathol 64:584–589
Keller AR, Hochholzer L, Castleman B (1972) Hyaline-vascular and plasma cell types of giant lymph node hyperplasia of the mediastinum and other locations. Cancer 29:670–683
Olscamp G, Weisbrod G, Sanders D, Delarue N, Mustard R (1980) Castleman disease: unusual manifestations of an unusual disorder. Radiology 135:43–48
Grossin M, Crickx B, Aitken G, Belaich S, Bocquet L (1985) Subcutaneous forms of the Castleman’s benign lymphoma: a case report with a review of the literature. Ann Dermatol Venereol 112:497–506
Culver GJ, Choi BK (1972) Benign lymphoid hyperplasia (Castleman’s tumor) mimicking a posterior mediastinal neurogenic tumor. Chest 62:516–517
Stanford WM, Givler R, Lawrence MS (1966) Mediastinal lymph node hyperplasia — report of a case with growth over an eight year period. J Thorac Cardiovasc Surg 52:303–308
Tuttle RJ, Shier KJ (1979) Angiography of angiomatous lymphoid hamartoma (Castleman tumor) and a suggested pathogenesis. Radiology 130:311–315
Katz I, Dziadiw R (1960) Localized mediastinal lymph node hyperplasia. Report of a case with roentgen findings simulating posterior mediastinal neurofibroma. AJR 84:206–212
Matsuoka K, Ito Y, Mizubuchi M, Nomura T, Kuwabara K, Okabayashi H, Iwata K, Kawashima K, Kasai T, Tsutsumi A (1975) So-called mediastinal lymph-node hyperplasia (Castleman). A case report with a review of the literature (in Japanese with English abstract). Kyobu Geka 28:813–820
Kambe S, Minato T, Toda K, Mitani S (1976) A case from Castleman-lymphoma discussed from etiological aspects (in Japanese with English abstract). Kyobu Geka 29:125–129
Mushiake T, Takaba T, Yamada S, Kawamura M, Michihata T, Yoshizawa T, Inoue K, Yamamoto N, Ishii J, Sugiyama Y (1983) An operated case of cystic Castleman-lymphoma in the mediastinum and the mechanism of its cystic formation (in Japanese with English abstract). Kyobu Geka 36:538–541
Fukumoto H, Kou K, Ohmori H, Kurata M, Ueda N, Sugiyama T (1983) Castleman’s lymphoma in the posterior mediastinum — report of a case with a brief review of the literature (in Japanese with English abstract). Rinsyo Kyobu Geka 3:499–503
Suto H, Suzuki Y, Azuma M, Hirai T, Sanpei Y, Niibe H, Honma M (1984) A case of Castleman’s lymphoma arising from posterior mediastinum (in Japanese with English abstract). Kitakantoh Igaku 34:469–474
Aihara M, Kudoh I, Tsushima Y, Morimoto S, Chiba Y, Yoshida Y, Kimura A, Sato I (1985) Castleman lymphoma associated with microangiopathic hemolytic anemia (in Japanese with English abstract). Rinsyo Ketsueki 26:577–581
Oura S, Kubo K, Hirai I, Nishimura Y, Yoshimura G, Kuwata T, Juri M, Nishiguchi T, Sakurai T, Nishiyama H, Sakamoto H (1989) A case of Castleman’s lymphoma in the posterior mediastinum (in Japanese with English abstract). J Wakayama Med Soc 40:343–347
Yamamoto N, Nomoto Y, Iwai N, Siba M, Ohnaka O, Kakizawa K, Kohno H, Yamaguchi Y, Ohwada H (1990) Posterior mediastinal Castleman disease (in Japanese with English abstract). Nippon Kyobu Rinsyo 49:227–230
Hamada F, Nishiyama Y, Fuziwara K, Takasu S, Inoue F, Orita K (1992) A case of mediastinal Castleman lymphoma (in Japanese with English abstract). Nippon Rinsyo Geka Igakkai Zasshi 53:2100–2103
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Iyoda, A., Yusa, T., Hiroshima, K. et al. Castleman’s disease in the posterior mediastinum: Report of a case. Surg Today 30, 473–476 (2000). https://doi.org/10.1007/s005950050629
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/s005950050629