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Densitometric evaluation in women with anorexia nervosa

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Abstract.

Anorexia nervosa (AN) is classified as a high-risk factor for osteoporotic fractures. Dual X-ray absorptiometry (DXA) is the most popular method for measuring bone loss, but it is less sensitive than quantitative computed tomography (QCT). We compared DXA and QCT in measuring the lumbar spine of 17 female patients with AN and 27 healthy subjects. We found discordance between DXA and QCT using World Health Organization (WHO) criteria with the T-score. With QCT as a reference method because of its sensitivity, we found one false-negative, one false-positive, and two misdiagnosed cases. We suggest some correction factors to improve DXA evaluation and screening of bone loss in AN.

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Authors and Affiliations

  1. Department of Radiology, University of Tor Vergata, Viale Oxford 81, I-00133, Rome, Italy

    S. Masala, R. Fiori, A. Marinetti & G. Simonetti

  2. Department of Endocrinology, University of Tor Vergata, Rome, Italy

    F. Jacoangeli & F. Staar Mezzasalma

  3. Department of Clinical Nutrition, University of Tor Vergata, Rome, Italy

    M. R. Bollea

Authors
  1. S. Masala
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  2. F. Jacoangeli
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  3. R. Fiori
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  4. F. Staar Mezzasalma
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  5. A. Marinetti
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  6. G. Simonetti
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  7. M. R. Bollea
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Corresponding author

Correspondence to S. Masala.

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Masala, S., Jacoangeli, F., Fiori, R. et al. Densitometric evaluation in women with anorexia nervosa. Acta Diabetol 40 (Suppl 1), s177–s179 (2003). https://doi.org/10.1007/s00592-003-0059-1

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  • DOI: https://doi.org/10.1007/s00592-003-0059-1

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