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A review on immunoglobulin Y (IgY) conjugated with metal nanoparticles and biomedical uses

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Abstract

Today, the use of nanoparticles has attracted considerable attention in biomedical investigations and applications. Antibody-nanoparticle conjugates have proven to be useful tools for raising accuracy and sensitivity in in vitro diagnostics. IgY antibodies have benefits over different antibodies in terms of minimizing animal harm, reducing reactivity with mammalian factors, and cost-effective extraction. Metal nanoparticles are widely used for various medical and biological applications and are potential candidates for identifying pathogens and treating them, which can be mostly related to their special properties, including their shape and size. Avian IgY antibodies conjugated with nanoparticles have been widely used for the detection of parasitic, viral, and bacterial infections as well as allergens and toxicological and pharmaceutical molecules. This review aimed to investigate avian antibodies conjugated with metal nanoparticles and their biological applications.

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Acknowledgements

We thank the Student Research Committee, Kerman University of Medical Sciences, (Kerman, Iran) for their support (98000727).

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Authors and Affiliations

  1. Medical Mycology and Bacteriology Research Center, Kerman University of Medical Sciences, Kerman, Iran

    Amin Sadeghi Dousari

  2. Faculty of Pharmacy, Kerman University of Medical Sciences, Kerman, Iran

    Seyed Soheil Hosseininasab & Naghmeh Satarzadeh

  3. School of Medicine, Zabol University of Medical Sciences, Zabol, Iran

    Majid Reza Akbarizadeh & Mahin Naderifar

  4. Research Center of Tropical and Infectious Diseases, Kerman University of Medical Sciences, Kerman, Iran

    Amin Mahdavi

  5. Student Research Committee, Faculty of Pharmacy, Kerman University of Medical Sciences, Kerman, Iran

    Naghmeh Satarzadeh

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  1. Amin Sadeghi Dousari
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  2. Seyed Soheil Hosseininasab
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Dousari, A.S., Hosseininasab, S.S., Akbarizadeh, M.R. et al. A review on immunoglobulin Y (IgY) conjugated with metal nanoparticles and biomedical uses. Bioprocess Biosyst Eng 46, 1533–1538 (2023). https://doi.org/10.1007/s00449-023-02909-x

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