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Multimodal imaging of linear lesions in the fundus of pathologic myopic eyes with macular lesions

  • Retinal Disorders
  • Published:
Graefe's Archive for Clinical and Experimental Ophthalmology Aims and scope Submit manuscript

Abstract

Purpose

To detect, using multimodal imaging, lacquer cracks (LCs) and myopic stretch lines (MSLs) in pathologic myopic eyes with macular hemorrhage (MHE) and those without.

Methods

We collected 18 consecutive pathologic myopic eyes (spherical equivalent ≤ −8.0 diopters) that had presented with linear, yellowish-white lesions in the macula. We categorized the eyes into either the MHE group or the non-MHE group. All underwent fluorescein angiography (FA), near infrared autofluorescence (NIA), indocyanine green angiography (ICGA), and spectral-domain optical coherence tomography (SD-OCT).

Results

In all 18 eyes, the linear lesions were hyperfluorescent under NIA imaging, but hypofluorescent under ICGA. All ten eyes in the MHE group had LCs, and two had both LCs and MSLs. None of the eight eyes in the non-MHE group had LCs. Regarding proximity to the MHE, LCs tended to locate closer than MSLs. Incidental perforating scleral vessels were clearly visible on the tracked SD-OCT scanning line, joining the choroid beneath the border of MHE. Sample cases are illustrated using delicate photographs and explanations.

Conclusion

NIA imaging combined with SD-OCT and ICGA can detect and differentiate early the subtle difference between the two types of linear lesions in pathological myopic eyes. Notably, MSLs were not associated with MHEs or LCs in our consecutive series.

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Acknowledgments

We appreciate all technicians from National Taiwan University Hospital for their technological support.

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Authors and Affiliations

  1. Department of Ophthalmology, National Taiwan University Hospital, College of Medicine, National Taiwan University, No. 7, Chung-Shan S. Rd., Taipei City, 10002, Taiwan, Republic of China

    Kuo-Chi Hung, Chung-May Yang, Shih-Wen Wang & Tzyy-Chang Ho

  2. Ministry of Health and Welfare, Department of Ophthalmology, Sinying Hospital, No.73, Xinyi St., Xinying Dist., Tainan City, 73042, Taiwan, Republic of China

    Kuo-Chi Hung

  3. Department of Ophthalmology, Cardinal Tien Hospital, Fu Jen Catholic University, No.362, Zhongzheng Rd., Xindian Dist., New Taipei City, 23148, Taiwan, Republic of China

    Muh-Shy Chen

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  1. Kuo-Chi Hung
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Correspondence to Tzyy-Chang Ho.

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All authors certify that they have no affiliations with or involvement in any organization or entity with any financial interest (such as honoraria; educational grants; participation in speakers’ bureaus; membership, employment, consultancies, stock ownership, or other equity interest; and expert testimony or patent-licensing arrangements), or non-financial interest (such as personal or professional relationships, affiliations, knowledge, or beliefs) in the subject matter or materials discussed in this manuscript.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

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Hung, KC., Chen, MS., Yang, CM. et al. Multimodal imaging of linear lesions in the fundus of pathologic myopic eyes with macular lesions. Graefes Arch Clin Exp Ophthalmol 256, 71–81 (2018). https://doi.org/10.1007/s00417-017-3833-4

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  • DOI: https://doi.org/10.1007/s00417-017-3833-4

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