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Acute pneumonitis and pericarditis related to alemtuzumab therapy in relapsing-remitting multiple sclerosis

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References

  1. Hartung H-P, Aktas O, Boyko AN (2015) Alemtuzumab: a new therapy for active relapsing–remitting multiple sclerosis. Mult Scler J 21(1):22–34

    Article  CAS  Google Scholar 

  2. Thomas K, Eisele J, Rodriguez-Leal FA et al (2016) Acute effects of alemtuzumab infusion in patients with active relapsing-remitting MS. Neurol Neuroimmunol Neuroinflamm 3(3):e228

    Article  PubMed  PubMed Central  Google Scholar 

  3. Wing MG, Moreau T, Greenwood J, Smith RM, Hale G et al (1996) Mechanism of first-dose cytokine-release syndrome by CAMPATH 1-H: involvement of CD16 (FcgammaRIII) and CD11a/CD18 (LFA-1) on NK cells. J Clin Invest 98(12):2819–2826

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Breslin S (2007) Cytokine-release syndrome: overview and nursing implications. Clin J Oncol Nurs 11:37–42

    Article  PubMed  Google Scholar 

  5. Maggi E, Vultaggio A, Matucci A (2011) Acute infusion reactions induced by monoclonal antibody therapy. Expert Rev Clin Immunol 7:55–63

    Article  CAS  PubMed  Google Scholar 

  6. Ruck Tobias, Bittner Stefan, Wiendl Heinz, Meuth Sven G (2015) Alemtuzumab in Multiple Sclerosis: mechanism of action and beyond. Int J Mol Sci 16:16414–16439

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  7. Moreau T, Coles A, Wing M, Isaacs J, Hale G, Waldmann H, Compston A (1996) Transient increase in symptoms associated with cytokine release in patients with multiple sclerosis. Brain 119(Pt 1):225–237

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Hospital Universitario Puerta de Hierro-Majadahonda, Manuel de Falla 1, Majadahonda, 28222, Madrid, Spain

    María Rosario Blasco, Antonio Ramos, Celia García Malo & Antonio García-Merino

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  1. María Rosario Blasco
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  2. Antonio Ramos
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  3. Celia García Malo
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  4. Antonio García-Merino
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Correspondence to María Rosario Blasco.

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None of the authors has any conflict of interest to disclose.

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All human studies must state that they have been approved by the appropriate ethics committee and have therefore been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki.

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Blasco, M.R., Ramos, A., Malo, C.G. et al. Acute pneumonitis and pericarditis related to alemtuzumab therapy in relapsing-remitting multiple sclerosis. J Neurol 264, 168–169 (2017). https://doi.org/10.1007/s00415-016-8306-x

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  • DOI: https://doi.org/10.1007/s00415-016-8306-x

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