Skip to main content

Advertisement

Log in

No evidence of increased oxidative degradation of urate to allantoin in the CSF and serum of patients with multiple sclerosis

  • LETTER TO THE EDITORS
  • Published:
Journal of Neurology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Drulovic J, Dujmovic I, Stojsavljevic N, Mesaros S, Andjelkovic S, Miljkovic D, Peric V, Dragutinovic G, Marinkovic J, Levic Z, Stojkovic MM (2001) Uric acid levels in sera from patients with multiple sclerosis. J Neurol 248:121–126

    CAS  PubMed  Google Scholar 

  2. Gilgun–Sherki Y,Melamed E, Offen D (2004) The role of oxidative stress in the pathogenesis of multiple sclerosis: The need for effective antioxidant therapy. J Neurol 251:261–268

    CAS  PubMed  Google Scholar 

  3. Hooper DC, Spitsin S, Kean RB, Champion JM, Dickson GM, Chaudhry I, Koprowski H (1998) Uric acid, a natural scavenger of peroxynitrite, in experimental allergic encephalomyelitis and multiple sclerosis. Proc Natl Acad Sci USA 95:675–680

    CAS  PubMed  Google Scholar 

  4. Karg E, Klivenyi P, Nemeth I, Bencsik K, Pinter S, Vecsei L (1999) Nonenzymatic antioxidants of blood in multiple sclerosis. J Neurol 246:533–539

    CAS  PubMed  Google Scholar 

  5. Kastenbauer S, Koedel U, Becker BF, Pfister HW (2002) Oxidative stress in bacterial meningitis in humans. Neurology 58:186–191

    CAS  PubMed  Google Scholar 

  6. Sotgiu S, Pugliatti M, Sanna A, Sotgiu A, Fois ML, Arru G, Rosati G (2002) Serum uric acid and multiple sclerosis. Neurol Sci 23:183–188

    CAS  PubMed  Google Scholar 

  7. Spitsin S,Hooper DC,Mikheeva T,Koprowski H (2001) Uric acid levels in patients with multiple sclerosis: analysis in mono- and dizygotic twins. Mult Scler 7:165–166

    CAS  PubMed  Google Scholar 

  8. Toncev G, Milicic B, Toncev S, Samardzic G (2002) Serum uric acid levels in multiple sclerosis patients correlate with activity of disease and blood-brain barrier dysfunction. Eur J Neurol 9:221–226

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to S. Kastenbauer.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kastenbauer, ., Kieseier, B.C. & Becker, B.F. No evidence of increased oxidative degradation of urate to allantoin in the CSF and serum of patients with multiple sclerosis. J Neurol 252, 611–612 (2005). https://doi.org/10.1007/s00415-005-0697-z

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00415-005-0697-z

Keywords

Navigation