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Population genetic analyses and evaluation of 22 autosomal STRs in Indian populations

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Abstract

The allele frequencies and forensically relevant parameters for the 22 autosomal short tandem repeats (STRs) present in PowerPlex® Fusion (Promega, Madison, WI) were determined for 357 unrelated individuals from 11 states across India. The combined power of discrimination and probability of exclusion were 0.99999999999999999999999999875 and 0.999999997200846, respectively. The panel was found to be informative for Indian populations and generated a total of 275 alleles. Further, analyses with these loci did not show any noticeable clustering among the Indian populations.

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Acknowledgements

We thank Promega Corporation for providing PowerPlex® Fusion reagents (Promega, Madison, WI, USA), Devinder Kumar for the sample collection, and Anujit Sarkar for the useful discussions. We are also grateful to all the volunteers for their participation in this study. This research was funded by core grants of Centre for DNA Fingerprinting and Diagnostics, India. M.S. was the recipient of Junior and Senior Research Fellowships of the Council of Scientific and Industrial Research (CSIR), India, towards the pursuit of a Ph.D. degree at the Manipal University, India.

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Authors and Affiliations

  1. Laboratory of Genomics and Profiling Applications, Centre for DNA Fingerprinting and Diagnostics, Hyderabad, Telangana, 500001, India

    Mugdha Singh & Madhusudan R. Nandineni

  2. Graduate Studies, Manipal University, Manipal, 576104, India

    Mugdha Singh

  3. Laboratory of DNA Fingerprinting Services, Centre for DNA Fingerprinting and Diagnostics, Hyderabad, Telangana, 500001, India

    Madhusudan R. Nandineni

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  1. Mugdha Singh
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Correspondence to Madhusudan R. Nandineni.

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Singh, M., Nandineni, M.R. Population genetic analyses and evaluation of 22 autosomal STRs in Indian populations. Int J Legal Med 131, 971–973 (2017). https://doi.org/10.1007/s00414-016-1525-y

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  • DOI: https://doi.org/10.1007/s00414-016-1525-y

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