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Carotid intima-media thickness and distensibility measured by MRI at 3 T versus high-resolution ultrasound

  • Magnetic Resonance
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Abstract

We evaluated an MRI protocol at 3 T for the assessment of morphological and functional properties of the common carotid artery (CCA) in 32 healthy volunteers and 20 patients with high-grade internal carotid artery stenosis. Wall thickness of the CCA was measured by using multislice 2D T2 dark blood fast spin echo sequences and compared with intima-media thickness (IMT) determined by ultrasound. Carotid distensibility coefficient (DC) quantified by blood pressure and CCA diameter change during the cardiac cycle was measured by ECG gated 3D T1 CINE MRI and M-mode ultrasound. Apart from generally higher values in MRI high agreement was found for wall thickness and compliance in volunteers and patients. Remaining differences between both methods may be attributed to slightly different methods for measuring IMT and DC. Our findings indicate that MRI at 3 T is a feasible and promising tool for the comprehensive assessment of normal carotid geometry and function.

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Authors and Affiliations

  1. Department of Neurology and Clinical Neurophysiology, University of Freiburg, Freiburg, Germany

    Andreas Harloff, Timo Zech & Cornelius Weiller

  2. Department of Radiology/Medical Physics, University of Freiburg, Freiburg, Germany

    Alex Frydrychowicz, Jürgen Hennig & Michael Markl

  3. Department of Neuroradiology, University of Freiburg, Freiburg, Germany

    Martin Schumacher

  4. Department of Cardiovascular Surgery, University of Freiburg, Freiburg, Germany

    Joachim Schöllhorn

  5. Department of Neurology and Clinical Neurophysiology, University of Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany

    Andreas Harloff

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  1. Andreas Harloff
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  2. Timo Zech
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  3. Alex Frydrychowicz
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  4. Martin Schumacher
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  7. Cornelius Weiller
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Correspondence to Andreas Harloff.

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Harloff, A., Zech, T., Frydrychowicz, A. et al. Carotid intima-media thickness and distensibility measured by MRI at 3 T versus high-resolution ultrasound. Eur Radiol 19, 1470–1479 (2009). https://doi.org/10.1007/s00330-009-1295-8

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  • DOI: https://doi.org/10.1007/s00330-009-1295-8

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