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The role of CD4+ T cell help in cancer immunity and the formulation of novel cancer vaccines

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Abstract

Recent years have seen the unprecedented surge of interest in the role of CD4+ T cells and the role they play in the development of the immune response. In this symposium review, we examine the evidence for this and discuss their functions, particularly in respect to the cancer immunology, including CD4+CD25+ cells (Treg).

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Authors and Affiliations

  1. School of Biomedical and Natural Sciences, Nottingham Trent University, Clifton lane, NG11 8NS, Nottingham, UK

    Deepak P. Assudani, Roger B. V. Horton, Morgan G. Mathieu, Stephanie E. B. McArdle & Robert C. Rees

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  1. Deepak P. Assudani
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  2. Roger B. V. Horton
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  3. Morgan G. Mathieu
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  4. Stephanie E. B. McArdle
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  5. Robert C. Rees
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Corresponding author

Correspondence to Robert C. Rees.

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This article is a symposium paper from the conference “Progress in Vaccination against Cancer 2005 (PIVAC 5)”, held in Athens, Greece, on 20–21 September 2005.

Deepak P. Assudani, Roger B.V. Horton and Morgan G. Mathieu are joint first authors and have contributed equally to this paper.

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Assudani, D.P., Horton, R.B.V., Mathieu, M.G. et al. The role of CD4+ T cell help in cancer immunity and the formulation of novel cancer vaccines. Cancer Immunol Immunother 56, 70–80 (2007). https://doi.org/10.1007/s00262-006-0154-6

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  • DOI: https://doi.org/10.1007/s00262-006-0154-6

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