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Gastric feed intolerance is not increased in critically ill patients with type II diabetes mellitus

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An Erratum to this article was published on 07 July 2007

Abstract

Objective

To examine the occurrence of feed intolerance in critically ill patients with previously diagnosed type II diabetes mellitus (DM) who received prolonged gastric feeding.

Design and setting

Retrospective study in a level 3 mixed ICU.

Patients

All mechanically ventilated, enterally fed patients (n = 649), with (n = 118) and without type II DM (n = 531) admitted between January 2003 and July 2005.

Interventions

Patients with at least 72 h of gastric feeding were identified by review of case notes and ICU charts. The proportion that developed feed intolerance was determined. All patient received insulin therapy.

Results

The proportion of patients requiring gastric feeding for at least 72 h was similar between patients with and without DM (42%, 50/118, vs. 42%, 222/531). Data from patients with DM were also compared with a group of 50 patients matched for age, sex and APACHE II score, selected from the total non-diabetic group. The occurrence of feed intolerance (DM 52% vs. matched non-DM 50% vs. unselected non-diabetic 58%) and the time taken to develop feed intolerance (DM 62.6 ± 43.8 h vs. matched non-DM 45.3 ± 54.6 vs. unselected non-diabetic 50.6 ± 59.5) were similar amongst the three groups. Feed intolerance was associated with a greater use of morphine/midazolam and vasopressor support, a lower feeding rate and a longer ICU length of stay.

Conclusions

In critically ill patients who require prolonged enteral nutrition, a prior history of DM type II does not appear to be a further risk factor for feed intolerance.

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Authors and Affiliations

  1. Department of Gastroenterology, Royal Adelaide Hospital, North Terrace, 5000, Adelaide, SA, Australia

    N. Q. Nguyen, K. Ching & R. H. Holloway

  2. Department of Intensive Care, Royal Adelaide Hospital, North Terrace, 5000, Adelaide, SA, Australia

    S. W. Lam & M. Chapman

  3. University Department of Medicine, Royal Adelaide Hospital, North Terrace, 5000, Adelaide, SA, Australia

    N. Q. Nguyen, R. J. Fraser & R. H. Holloway

  4. Department of Gastroenterology, Repatriation General Hospital, 5041, Adelaide, SA, Australia

    R. J. Fraser

Authors
  1. N. Q. Nguyen
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  2. S. W. Lam
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  3. K. Ching
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  4. M. Chapman
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  5. R. J. Fraser
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  6. R. H. Holloway
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Corresponding author

Correspondence to N. Q. Nguyen.

Additional information

This research was supported by the National Health and Medical Research Council of Australia

An erratum to this article can be found at http://dx.doi.org/10.1007/s00134-007-0777-x

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Nguyen, N.Q., Lam, S.W., Ching, K. et al. Gastric feed intolerance is not increased in critically ill patients with type II diabetes mellitus . Intensive Care Med 33, 1740–1745 (2007). https://doi.org/10.1007/s00134-007-0712-1

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  • DOI: https://doi.org/10.1007/s00134-007-0712-1

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