Abstract
A 20-year-old Japanese female anorectic patient developed primary hypothy roidism associated with generalized edema because of excessive daily intake (40 to 50 g) o confectionery made with tangle weed, Kombu, which she substituted to food during bulimic periods; TSH 60.35 mcU/ml, free T3 1.19 pg/ml, and free T4 0.48 ng/dl, and her weigh increased by 12 kg to 45 kg over 4 months. After withdrawal of Kombu her thyroid function returned to normal, and her weight decreased by 7 kg to 38 kg along with disappearance o edema. In conclusion, the physician noticed that susceptible anorectic patients may sometime develop hypothyroidism or hyperthyroidism because of excessive iodine intake of sea-weed confectionery as a substitute of high calorie cakes during bulimic period.
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Matsubayashi, S., Mukuta, T., Watanabe, H. et al. Iodine-induced hypothyroidism as a result of excessive intake of confectionery made with tangle weed, Kombu, used as a low calorie food during a bulimic period in a patient with anorexia nervosa. Eat Weight Disord 3, 50–52 (1998). https://doi.org/10.1007/BF03339988
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DOI: https://doi.org/10.1007/BF03339988