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Genetical studies on the skeleton of the mouse

VIII. Curly-tail

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Summary

Curly-tail is probably due to a single recessive gene whose manifestation is greatly influenced by the genetic background. The tail anomalies are produced mechanically either by spina bifida which persists, or by a rudimentary form of it (delayed closure of the posterior neuropore) which is transitory.

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References

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Authors and Affiliations

  1. University College, London

    Hans Grüneberg

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  1. Hans Grüneberg
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Additional information

I am greatly indebted to Dr W. F. B. Cuthbertson, of the Glaxo Laboratories, Greenford, Middlesex, for the gift of the original curly-tail mice. My thanks are also due to my colleague, Dr A. G. Searle, for his assistance in the collection of the embryonic material during my visit to the U.S.A. in the summer of 1952. The work reported in this paper has been supported by grants from the Medical Research Council and from the Rockefeller Foundation which are gratefully acknowledged.

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Grüneberg, H. Genetical studies on the skeleton of the mouse. Journ. of Genetics 52, 52–67 (1954). https://doi.org/10.1007/BF02981490

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  • DOI: https://doi.org/10.1007/BF02981490

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