Skip to main content
Log in

Approach to renal tubular disorders

  • Symposium on Pediatria Nephrology
  • Published:
The Indian Journal of Pediatrics Aims and scope Submit manuscript

Abstract

The renal tubule plays an important role in fluid and electrolyte homeostasis. Renal tubular disorders may affect multiple (e.g., Fanconi syndrome) or specific (e.g., nephrogenic diabetes insipidus, renal glucosuria) tubular functions. Most conditions are primary and monogenic but occasionally are secondary to other disorders (focal segmentai glomerulosclerosis, cystinosis, Lowe syndrome). Tubular dysfunction should be considered in all children with failure to thrive, polyuria, refractory rickets, hypokalemia and metabolic acidosis. Careful clinical and laboratory evaluation is essential for appropriate diagnosis and specific management of these conditions.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Rodriguez-Soriano J. Tubular disorders of electrolyte regulation. In Avner ED, Harmon WE, Niaudet P, eds.Pediatric Nephrology. 5th edn. Baltimore; Lippincot Williams & Wilkins, 2004: 729–756.

    Google Scholar 

  2. Van’t Hoff W. Renal tubular disorders. In Webb NJ, Postlethwaite RJ, eds.Clinical Pediatric Nephrology. 3rd edn. New York; Oxford Press, 2003: 103–112.

    Google Scholar 

  3. Herrin TJ. Renal tubular acidosis. In Avner ED, Harmon WE, Niaudet P, eds.Pediatriec Nephrology. 5th edn. Baltimore; Lippincot Williams & Wilkins, 2004: 757–776.

    Google Scholar 

  4. Walton RJ, Bijvoet OL. Nomogram for the derivation of renal tubular threshold concentration.Lancet 1975; 2: 309–310.

    Article  PubMed  CAS  Google Scholar 

  5. Postlethwaite RJ. The approach to a child with metabolic acidosis or alkalosis. In Webb NJ, Postlethwaite RJ, eds.Clinical Pediatric Nephrology. 3rd edn. New York; Oxford Press 2003: 61–72.

    Google Scholar 

  6. Jones C, Mughal Z. Disorders of mineral metabolism and nephrocalcinosis. In Webb NJA, Postlethwaite RJ, eds.Clinical Pediatric Nephrology. 3rd edn. New York; Oxford Press, 2003: 73–102.

    Google Scholar 

  7. Muglia LJ. Majzoub JA. Disorders of the posterior pituitary. In Sperling MA, eds.Pediatric Endocrinology. 2nd edn. Philadelphia; WB Saunders, 2000; 289–322.

    Google Scholar 

  8. Diabetes insipidus. In Bajpai A, Sharma J, Menon PSN, eds.Practical Pediatric Endocrinology. 1st edn. New Delhi; Jaypee 2003: 17–23.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Arvind Bagga.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bagga, A., Bajpai, A. & Menon, S. Approach to renal tubular disorders. Indian J Pediatr 72, 771–776 (2005). https://doi.org/10.1007/BF02734150

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02734150

Key words

Navigation