Summary
A 38-year-old Omani woman, seven months pregnant, developed extensive zygomycosis involving maxillary and temporal bones. No evidence of any underlying immune deficiency was detected except that which may be attributed to pregnancy. After delivery the patient was treated with repeated courses of amphotericin B, which resulted in a complete clinical resolution. Zygomycosis in uncomplicated pregnancy has not been previously described.
Zusammenfassung
Eine 38jährige Frau aus dem Sultanat Oman entwickelte im siebten Schwangerschaftsmonat eine Zygomykose, die die Oberkiefer-und Schläfenknochen befiel. Es bestand kein Anhalt für über die schwangerschaftsassoziierte Beeinträchtigung der Abwehrlage hinaus bestehende Immunstörungen. Nach der Entbindung wurde die Patientin erfolgreich mit Amphotericin B behandelt und eine komplette klinische Wiederherstellung erreicht. Bisher liegen keine Berichte über eine Zygomykose bei unkomplizierter Schwangerschaft vor.
Similar content being viewed by others
References
Meyer, R. D. Agents of mucormycosis and related species. In:Mandell, G. L., Douglas, R. G., Bennett, J. E. (eds.): Principles and practice of infectious diseases, 2nd edition. Wiley Medical Publications, New York 1985, pp. 1452–1456.
Rippon, J. W. Zygomycosis. In: Medical mycology, 3rd edition. W. B. Saunders, Philadelphia 1988, pp. 681–713.
Taylor, C. G., Alexander, R. E., Green, W. H., Kramer, H. S. Mucormycosis involving the maxilla. Oral Surg. Oral Med. Oral Pathol. 27 (1969) 806–822.
Tabachnic, T. T., Levine, B. Mucormycosis of the craniofacial structures. J. Oral Surg. 33 (1975) 464–469.
Weems, J. J., Davis, B. J., Tablan, O. C., Kautman, L., Martone, W. J. Construction activity: an independent risk factor for invasive aspergillosis and zygomycosis in patients with haematological malignancy. Infect. Control 8 (1987) 71–75.
Cohen, J. Laboratory monitoring of antifungal chemotherapy. Lancet 337 (1991) 1577–1580.
Bullen, J. J. The significance of iron in infection. Rev. Infect. Dis. 3 (1981) 1127–1138.
Norden, G., Bjork, S., Persson, H., Svalander, C., Li, X. E., Debo, L. Cure of zygomycosis caused by a lipase-producingRhizopus rhizopodiformis strain in a renal transplant patient. Scand. J. Infect. Dis. 23 (1991) 377–382.
Sande, M. A., Mandell, G. L. Antifungal agents. In:Gilman, A. G., Goodman, L. S., Rall, T. W., Murad, F. (eds.): The pharmacological basis of therapeutics, 7th edition. Macmillan Publishing Co., New York 1985, pp. 1219–1223.
McLean, A. B. Infection and the antinatal patient. In:MacLean, A. B. (ed.): Clinical infections in obstetrics and gynaecology. Blackwell Scientific Publications, Oxford 1990, pp. 21–39.
Vleugels, M. P. H., Eling, W. M. C., Rolland, R., De Graayy, R. Cortisol and loss of malaria immunity in human pregnancy. Br. J. Obstet. Gynaecol. 94 (1987) 758–764.
Manson-Bahr, P. E. C., Bell, D. R. Malaria and babesiosis. In:Manson-Bahr, P. E. C., Bell, D. R. (eds.): Manson's tropical diseases. Baillière Tindall, London 1987, pp. 25–26.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Buhl, M.R., Joseph, T.P., Buhl, L. et al. Temporofacial zygomycosis in a pregnant woman. Infection 20, 230–232 (1992). https://doi.org/10.1007/BF02033066
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02033066