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Klebsiella oxytoca meningitis: Frequent association with neurosurgical procedures

Klebsiella oxytoca-Meningitis: Häufige Assoziation mit neurochirurgischen Eingriffen

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Summary

Klebsiella oxytoca meningitis is a rare condition. Nine patients were diagnosed between 1981 and 1993 at our institution. These accounted for 2.3% of 393 patients with blood and/or cerebrospinal fluid culture-proven bacterial meningitis.K. oxytoca was noted in both community-acquired meningitis and nosocomial meningitis. Eight of the nine cases were patients who had undergone neurosurgical procedures. Four were mixed bacterial meningitis. AllK. oxytoca isolates were susceptible to third-generation cephalosporins and all but one to chloramphenicol. Antibiotic therapy was successful in eight patients but failed in one.

Zusammenfassung

DieKlebsiella oxytoca-Meningitis ist eine seltene Erkrankung. Zwischen 1981 und 1993 wurden in unserer Klinik neun Fälle diagnostiziert, entsprechend 2,3% von 393 Patienten mit mikrobiologisch durch positive Blut- oder Liquorkulturen belegter bakterieller Meningitis.K. oxytoca wurden sowohl bei ambulant erworbener wie bei nosokomialer Meningitis beobachtet. Acht der neun Fälle betrafen Patienten, die einen neurochirurgischen Eingriff durchgemacht hatten. In vier Fällen lag eine Mischinfektion vor. AlleK. oxytoca-Isolate waren empfindlich gegen Cephalosporine der dritten Generation und mit einer Ausnahme auch gegen Chloramphenicol. Die Antibiotikatherapie war in acht Fällen erfolgreich und versagte in einem Fall.

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Authors and Affiliations

  1. Dept. of Neurology, Chang Gung Memorial Hospital and Medical College, 199 Tung Hwa North Rd., Taipei, Taiwan

    L. -M. Tang M. D., M. Sc. & S. -T. Chen M. D.

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  1. L. -M. Tang M. D., M. Sc.
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  2. S. -T. Chen M. D.
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Tang, L.M., Chen, S.T. Klebsiella oxytoca meningitis: Frequent association with neurosurgical procedures. Infection 23, 163–167 (1995). https://doi.org/10.1007/BF01793857

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