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Analogs of pyrimidine nucleosides

IV. The silyl method of obtaining N1-(α-tetrahydrofuryl) and N1-(α-tetrahydropyranyl) derivatives of uracils and 6-azauracil

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Abstract

N1-(α-Tetrahydrofuranyl)- and N1-(α-tetrahydropyranyl)uracils and the corresponding 6-azauracils have been obtained by the condensation of bistrimethylsilyl derivatives of uracils and 6-azauracils withα-chlorotetrahydrofuran andα-chlorotetrahydropyran. The superiority of the “silyl” method over the “mercury” method used previously has been demonstrated.

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References

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Authors and Affiliations

  1. Institute of Organic Synthesis AS LatvSSR, Riga

    S. A. Hiller, M. Yu. Lidak, R. A. Zhuk, A. E. Berzinya, K. Ya. Pets, I. N. Getsova & E. I. Bruk

Authors
  1. S. A. Hiller
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  2. M. Yu. Lidak
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  3. R. A. Zhuk
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  4. A. E. Berzinya
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  5. K. Ya. Pets
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  6. I. N. Getsova
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  7. E. I. Bruk
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Additional information

For part III, see [9].

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Hiller, S.A., Lidak, M.Y., Zhuk, R.A. et al. Analogs of pyrimidine nucleosides. Chem Heterocycl Compd 5, 283–285 (1969). https://doi.org/10.1007/BF00943946

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  • DOI: https://doi.org/10.1007/BF00943946

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