Abstract
The sleep-wake cycle and the circadian rhythm of rectal temperature were recorded in subjects who lived singly in an isolation unit. In 10 subjects, the freerunning rhythms remained internally synchronized, 10 other subjects showed internal desynchronization. Times of onset and end of bedrest (“sleep”) were determined in each cycle and referred to the phase of the temperature rhythm. In the synchronized subjects, onset of sleep occurred, on the average, 1.34 h before the minimum of temperature, and end of sleep 6.94 h thereafter, with narrow distributions. The desynchronized subjects had a broad bimodal distribution of sleep onsets (peaks 6.3 and 1.3 h before the minimum); the duration of sleep varied between more than 15 h when sleep began about 10 h before the temperature minimum, and less than 4 h when sleep began several hours after the minimum. The dependence of sleep duration on body temperature is interpreted as a continuing action of the coupling forces between the two rhythms after mutual synchronization is lost.
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References
Aschoff J (1944) Über die Interferenz temperaturregulatorischer und kreislaufregulatorischer Vorgänge in den Extremitäten des Menschen. Pflügers Arch Ges Physiol 248:197–207
Aschoff J (1970) Circadian rhythms of activity and of body temperature. In: Hardy JD, Gagge AP, Stolwijk JAJ (eds) Physiological and behavioral temperature regulation. Ch C Thomas Publ, Springfield Illinois, pp 905–919
Aschoff J (1981a) Circadian rhythms: interference with an dependence on work-rest schedules. In: Johnson LC, Tepas DI, Colquhoun WP, Colligan MJ (eds) Biological rhythms and shift work. Advances in sleep research vol 7. Spectrum Publications, New York (in press)
Aschoff J (1981b) Circadian system properties. In: Obal F, Benedek K (eds) Advances in physiological sciences, vol 18. Environmental physiology. Akademiai Kiadé, Budapest, pp 1–17
Aschoff J (1981c) Disorders of the circadian system as discussed in psychiatric research. In: Wehr TA, Goodwin FK (eds Circadian rhythms in psychiatry. Boxwood Press, Neuroscience Series, Los Angeles (in press)
Aschoff J, Wever R (1980) Über Reproduzierbarkeit circadianer Rhythmen beim Menschen. Klin Wochenschr 58:323–335
Aschoff J, Gerecke U, Wever R (1967a) Desynchronization of human circadian rhythms. Jpn J Physiol 17:450–457
Aschoff J, Gerecke U, Wever R (1967b) Phasenbeziehungen zwischen den circadianen Perioden der Aktivität und der Kerntemperatur beim Menschen. Pflügers Arch 295:173–183
Aschoff J, Pöppel E, Wever R (1969) Circadiane Periodik des Menschen unter dem Einfluß von Licht-Dunkel-Wechseln unterschiedlicher Periode. Pflügers Arch 306:58–70
Czeisler CA (1978) Human circadian physiology: internal organization of temperature, sleep-wake, and neuroendocrine rhythms monitored in an environment free of time cues. Ph D Thesis, Stanford University
Czeisler CA, Weitzman ED, Moore-Ede MC, Zimmerman JC, Knauer RS (1980a) Human sleep: Its duration and organization depend on its circadian phase. Science 210:1264–1267
Czeisler CA, Zimmerman JC, Ronda JM, Moore-Ede MC, Weitzman ED (1980b) Timing of REM sleep is coupled to the circadian rhythm of body temperature in man. Sleep 2:329–346
Heller HC (1977) Thermoregulation during sleep hibernation. In: Robertshaw D (ed) International review of physiology: Environmental physiology II, vol 15. University Park Press, Baltimore, pp 179–188
Kiloh LG, Garside RF (1963) The independence of neurotic depression and endogenous depression. Br J Psychiat 109:451–463
Kleitman N, Doktorsky A (1933) The effects of the position of the body and of sleep on rectal temperature in man. Am J Physiol 104:340–343
Kripke DF, Mullaney DJ, Atkinson ML, Huey LY, Hubbard B (1979) Circadian rhythm phases in affective illnesses. Chronobiologia 6:365–375
Pflug B, Martin W (1980) Analyse circadianer Temperaturgänge bei endogener Depression. Arch Psychiat Nervenkr 229:127–143
Wehr ThA, Muscetolla G, Goodwin FK (1980) Urinary 2-methoxy-4-hydroxyphenylglycol circadian rhythm. Arch Gen Psychiatry 37:257–263
Wehr ThA, Wirz-Justice A, Goodwin FK, Duncan W, Gillin JCh (1979) Phase advance of the circadian sleep-wake cycle as an antidepressant. Science 206:710–713
Wever R (1972) Mutual relations between different physiological functions in circadian rhythms in man. J Interdiscipl Cycle Res 3:253–265
Wever R (1979) The circadian system of man. Springer, Berlin Heidelberg New York
Zulley J (1976) Schlaf und Temperatur unter freilaufenden Bedingungen. In: Bericht über den 30. Kongress der dtsch Ges für Psychol. Hogrefe, Göttingen, pp 398–399
Zulley J, Schulz H (1980) Sleep and body temperature in free-running sleep-wake cycles. In: Sleep 1978. Fourth European Congress on Sleep Research, Tirgu Mures. S Karger, Basel, pp 341–344
Zulley, J, Wever R (1982) Interaction between the sleep-wake cycle and the rhythm of rectal temperature. In: Aschoff J, Daan S, Groos G (eds) Vertebrate circadian systems: structure and physiology. Springer, New York Heidelberg Berlin (in press)
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Dedicated to Prof. Dr. Rudolf Thauer on the occasion of his 75th birthday
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Zulley, J., Wever, R. & Aschoff, J. The dependence of onset and duration of sleep on the circadian rhythm of rectal temperature. Pflugers Arch. 391, 314–318 (1981). https://doi.org/10.1007/BF00581514
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DOI: https://doi.org/10.1007/BF00581514