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Ovine platelet function and its inhibition by T-2 toxin

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Abstract

Ovine platelets suspended in homologous plasma aggregated effectively in response to adenosine-diphosphate, acid-soluble collagen and aggregated moderately to serotonin and arachidonic acid. Ovine platelet aggregation, in response to each agent, was inhibited in a concentration dependent fashion by T-2 toxin. The platelet aggregates which formed in the presence of T-2 toxin appeared to be less stable than aggregates in comparable control platelet suspensions.

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Authors and Affiliations

  1. Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, N1G 2W1, Guelph, Ontario, Canada

    P. A. Gentry, A. S. Socha & M. L. Ross

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  1. P. A. Gentry
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  2. A. S. Socha
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  3. M. L. Ross
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Gentry, P.A., Socha, A.S. & Ross, M.L. Ovine platelet function and its inhibition by T-2 toxin. Vet Res Commun 11, 457–466 (1987). https://doi.org/10.1007/BF00380628

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