Skip to main content
SpringerLink
Log in

Generalized dermal perifollicular fibromas with polyps of the colon

  • Clinical Case Reports
  • Published:
Human Genetics Aims and scope Submit manuscript

Summary

The cases of 2 siblings with a rare, generalized genodermatosis have been reported, the most conspicuous feature being multiple perifollicular fibromas. In this type of dermal hamartomas, an apparent autosomal dominant trait was noted as well as the association with a small number of colon polyps in one of the patients. The author assumes a distinct dermo-intestinal syndrome not reported hitherto, which can be differentiated from Gardner's syndrome.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • Burnier, Rejsek: Fibromes sous-cutanés péripilaires multiples du cou. Bull. Soc. franç. Derm. 32, 242–243 (1925)

    Google Scholar 

  • Civatte, J., Tréguilly, J.-P.: Fibromes périfolliculaires multiples du visage et du cou. Bull. Soc. franç. Derm. Syph. 78, 100–103 (1971)

    Google Scholar 

  • Duperrat, P. B., Menanteau, Y.: Le fibrome périfolliculaire. Ann. Derm. Syph. (Paris) 96, 121–128 (1969)

    Google Scholar 

  • Gardner, E. J.: Follow-up study of a family group exhibiting dominant inheritance for a syndrome including intestinal polyps, osteomas, fibromas and epidermal cysts. Amer. J. hum. Genet. 14, 376–390 (1962)

    Google Scholar 

  • Gardner, E. J., Richards, R. C.: Multiple cutaneous and subcutaneous lesions occurring simultaneously with hereditary polyposis and osteomatosis. Amer. J. hum. Genet. 5, 139–147 (1953)

    Google Scholar 

  • Hornstein, O. P., Knickenberg, M.: Perifollicular fibromatosis cutis with polyps of the colon—a cutaneo-intestinal syndrome sui generis. Arch. Derm. Res. 253, 161–175 (1975)

    Google Scholar 

  • Hornstein, O. P., Knickenberg, M., Mörl, M.: Multiple dermal perifollicular fibromas with polyps of the colon—Report of a peculiar clinical syndrome. Acta hepato-gastroenterol. 23, 53–58 (1976)

    Google Scholar 

  • Weary, E. P., Gorlin, R. J., Gentry, W. C. Jr., Comer, J. E., Greer, K. E.: Multiple hamartoma syndrome (Cowden's disease). Arch. Derm. 106, 682–690 (1972)

    Google Scholar 

  • Weary, P. E., Linthicum, A., Cawley, E. P., Graham, G. F.: Gardner's syndrome. A family group study and review. Arch. Derm. 90, 20–30 (1964)

    Google Scholar 

  • Zackheim, H. S., Pinkus, H.: Perifollicular fibromas. Arch. Derm. 82, 913–917 (1960)

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Dermatology, University of Erlangen-Nuremberg, Erlangen, Germany

    O. P. Hornstein

Authors
  1. O. P. Hornstein
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Hornstein, O.P. Generalized dermal perifollicular fibromas with polyps of the colon. Hum Genet 33, 193–197 (1976). https://doi.org/10.1007/BF00281897

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00281897

Keywords

Search

Navigation