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Manufacturing of Biologics

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Biologic and Systemic Agents in Dermatology

Abstract

Biologics have brought a new dimension to the treatment of chronic diseases. As compared to small molecules, biologics are created in living cells and thus the manufacturing of biologics is a complex process. This chapter discusses the multistep approach used to manufacture biotechnology-derived biologics. The chapter also discusses biosimilars and the complexity of their development and manufacturing along with highlighting the differences between two often-confused terms—biosimilarity and comparability.

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Author information

Authors and Affiliations

  1. Biosimilars Development, Amgen Inc, Thousand Oaks, CA, USA

    Jared J. Nathan BS chemistry, Monica Ramchandani BS, MS, PhD & Primal Kaur MD, MBA

Authors
  1. Jared J. Nathan BS chemistry
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  2. Monica Ramchandani BS, MS, PhD
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  3. Primal Kaur MD, MBA
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Corresponding author

Correspondence to Primal Kaur MD, MBA .

Editor information

Editors and Affiliations

  1. Division of Dermatology, David Geffen School of Medicine a UCLA, Los Angeles, California, USA

    Paul S. Yamauchi

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Nathan, J.J., Ramchandani, M., Kaur, P. (2018). Manufacturing of Biologics. In: Yamauchi, P. (eds) Biologic and Systemic Agents in Dermatology. Springer, Cham. https://doi.org/10.1007/978-3-319-66884-0_12

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  • DOI: https://doi.org/10.1007/978-3-319-66884-0_12

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-66883-3

  • Online ISBN: 978-3-319-66884-0

  • eBook Packages: MedicineMedicine (R0)

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