Skip to main content

Passerini Reaction

  • Chapter
  • First Online:
Name Reactions

Abstract

Three-component condensation (3CC), one of the multicomponent reactions (MCRs), of carboxylic acids, C-isocyanides, and carbonyl compounds to afford α-acyloxycarboxamides. Also known as three-component reaction (3CR). Cf. Ugi reaction.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 59.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 79.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 119.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. 1.

    Passerini, M. Gazz. Chim. Ital. 1921, 51, 126-129. (b) Passerini, M. Gazz. Chim. Ital. 1921, 51, 181-188. Mario Passerini (1891-1962) was born in Scandicci, Italy. He obtained his Ph.D. in chemistry and pharmacy at the University of Florence, where he was a professor for most of his career.

  2. 2.

    Ferosie, I. Aldrichimica Acta 1971, 4, 21. (Review).

  3. 3.

    Barrett, A. G. M.; Barton, D. H. R.; Falck, J. R.; Papaioannou, D.; Widdowson, D. A. J. Chem. Soc., Perkin Trans. 1 1979, 652-661.

  4. 4.

    Ugi, I.; Lohberger, S.; Karl, R. In Comprehensive Organic Synthesis; Trost, B. M.; Fleming, I., Eds.; Pergamon: Oxford, 1991, Vol. 2, p.1083. (Review).

  5. 5.

    Bock, H.; Ugi, I. J. Prakt. Chem. 1997, 339, 385-389.

  6. 6.

    Banfi, L.; Guanti, G.; Riva, R. Chem. Commun. 2000, 985–986.

  7. 7.

    Owens, T. D.; Semple, J. E. Org. Lett. 2001, 3, 3301–3304.

  8. 8.

    Xia, Q.; Ganem, B. Org. Lett. 2002, 4, 1631-1634.

  9. 9.

    Banfi, L.; Riva, R. Org. React. 2005, 65, 1-140. (Review).

  10. 10.

    Klein, J. C.; Williams, D. R. Passerini Reaction. In Name Reactions for Homologations-Part II; Li, J. J., Ed.; Wiley: Hoboken, NJ, 2009, pp 765-785. (Review).

  11. 11.

    Sato, K.; Ozu, T.; Takenaga, N. Tetrahedron Lett. 2013, 54, 661–664.

  12. 12.

    Vlahoviček-Kahlina, K.; Vazdar, M.; Jakas, A.; Smrečki, V.; Jerić, I. J. Org. Chem. 2018, 83, 13146–13156.

  13. 13.

    Liu, N.; Chao, F.; Liu, M.-G.; Huang, N.-Y.; Zou, K.; Wang, L. J. Org. Chem. 2019, 84, 2366–2371.

  14. 14.

    So, W. H.; Xia, J. Org. Lett. 2020, 22, 214–218.

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 2021 Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Li, J.J. (2021). Passerini Reaction. In: Name Reactions. Springer, Cham. https://doi.org/10.1007/978-3-030-50865-4_115

Download citation

Publish with us

Policies and ethics