Abstract
Gene therapy has emerged as a potential avenue of treatment for many neurological disorders. Technological advances in imaging techniques allow for the monitoring of real-time infusions into the brain of rodents, nonhuman primates, and humans. Here, we discuss the use of magnetic resonance imaging (MRI) as a tool in the delivery of adeno-associated viral (AAV) particles into brain of nonhuman primates.
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Acknowledgement
This work was supported by a grant to K.S.B. from NIH-NINDS (R01NS073940-01).
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Salegio, E.A., Bringas, J., Bankiewicz, K.S. (2016). MRI-Guided Delivery of Viral Vectors. In: Manfredsson, F. (eds) Gene Therapy for Neurological Disorders. Methods in Molecular Biology, vol 1382. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-3271-9_15
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DOI: https://doi.org/10.1007/978-1-4939-3271-9_15
Publisher Name: Humana Press, New York, NY
Print ISBN: 978-1-4939-3270-2
Online ISBN: 978-1-4939-3271-9
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