Summary
Cardiac-type fatty acid-binding protein (cFABP) from human heart muscle of three individuals was isolated and characterized as pi 5.3-cFABP. The proteins were structurally analyzed by tryptic peptide mapping, application of plasma desorption time-of-flight mass spectrometry and amino acid sequencing. All three preparations of human heart FABP, having 132 amino acids, differed from the published sequence [Offner et al. Biochem J 251: 191–198, 1988] in position 104, where Leu is found instead of Lys, and in position 124, where Cys is found instead of Ser.
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References
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© 1990 Springer Science+Business Media Dordrecht
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Börchers, T., Højrup, P., Nielsen, S.U., Roepstorff, P., Spener, F., Knudsen, J. (1990). Revision of the amino acid sequence of human heart fatty acid-binding protein. In: Glatz, J.F.C., Van Der Vusse, G.J. (eds) Cellular Fatty Acid-binding Proteins. Developments in Molecular and Cellular Biochemistry, vol 6. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3936-0_16
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DOI: https://doi.org/10.1007/978-1-4615-3936-0_16
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