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Micro-FE Analyses of Bone: State of the Art

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Book cover Noninvasive Assessment of Trabecular Bone Architecture and the Competence of Bone

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 496))

Abstract

Micro-finite element (µFE) analysis is a numerical technique to calculate mechanical properties of trabecular bone as they relate to its micro-structure. It is based on two recent developments. The first is a method for the three-dimensional graphics computer reconstruction of trabecular structure. With this method, high-resolution images of sequential cross-sections of a trabecular bone region are created. These images are digitized and stored in a computer. By stacking the cross-sectional images the original structure can be rebuild in the computer as a three-dimensional voxel (i.e. 3-D pixel) grid. Methods to create the high-resolution images can be destructive (e.g. serial sectioning and serial milling techniques1,2) or non-destructive (e.g. µCT and µMR imaging3,4.5,6) In both cases a resolution of 50 microns or better can usually be achieved for trabecular bone regions of approximately 1 cm3in size.

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Authors and Affiliations

  1. Department of Biomedical Engineering, Eindhoven University of Technology, P.O. Box 513, Eindhoven, 5600 MB, The Netherlands

    Bert van Rietbergen

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  1. Bert van Rietbergen
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Editors and Affiliations

  1. Magnetic Resonance Science Center Department of Radiology, University of California, San Francisco, San Francisco, California, USA

    Sharmila Majumdar Ph.D.

  2. Department of Mechanical Engineering and Department of Exercise and Sport Medicine, Oregon State University, Corvallis, Oregon, USA

    Brian K. Bay Ph.D.

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van Rietbergen, B. (2001). Micro-FE Analyses of Bone: State of the Art. In: Majumdar, S., Bay, B.K. (eds) Noninvasive Assessment of Trabecular Bone Architecture and the Competence of Bone. Advances in Experimental Medicine and Biology, vol 496. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-0651-5_3

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  • DOI: https://doi.org/10.1007/978-1-4615-0651-5_3

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5177-1

  • Online ISBN: 978-1-4615-0651-5

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