Regular ArticleElectrochemical Detection of Nucleic Base Mismatches with Ferrocenyl Naphthalene Diimide
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Detection of an aberrant methylation of CDH4 gene in PCR product by ferrocenylnaphthalene diimide-based electrochemical hybridization assay
2012, Analytica Chimica ActaCitation Excerpt :However, such quantitative analyses have not been achieved for PCR products as target DNA though electrochemical detection of PCR product is required to develop the portable DNA chip for practical use [2,6,7,17,19,22]. We have been studying the ferrocenylnaphthalene diimide (FND)-based hybridization assay because FND generated stable signal after hybridization of double stranded DNA region on the electrode [6–13]. Here, we report study of the hybridization efficiency of oligonucleotides and PCR products with DNA probe-immobilized electrode.
Spectroscopic characterizations on the N,N'-bis-alkyl derivatives of 1,4,6,8-naphthalenediimide charge-transfer complexes
2011, Arabian Journal of ChemistryElectrochemical detection of aberrant methylated gene using naphthalene diimide derivative carrying four ferrocene moieties
2010, Journal of Organometallic ChemistryCitation Excerpt :The relatively good hybridization efficiency achieved in our case comes probably from the stabilization effect of F4ND threading intercalation on double stranded DNA. This ligand could stabilize DNA duplex and the stabilization extent of fully matched combination was higher than that of mismatched combination, which is in agreement with the case of FND [35]. The Δi values obtained in this experiment allowed discrimination between fully matched and mismatched combinations within the error, although, scattered results were observed for the individual electrodes.
Spectroscopic and structural characterization of the charge-transfer interaction of N,N′-bis-alkyl derivatives of 1,4,6,8-naphthalenediimide with chloranilic and picric acids
2008, Spectrochimica Acta - Part A: Molecular and Biomolecular SpectroscopyFerrocenylnaphthalene diimide-based electrochemical detection of methylated gene
2006, Analytica Chimica ActaSpectral properties of new N,N′-bis-alkyl-1,4,6,8-naphthalenediimide complexes
2006, Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy
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